895570-99-7

Basic information

• Product Name: (2R,3R)-2-benzylamino-3-(4-methylsulfonylphenyl)-propane-1,3-diol
• Synonyms: (2R,3R)-2-benzylamino-3-(4-methylsulfonylphenyl)-propane-1,3-diol
• CAS NO: 895570-99-7
• Molecular Weight: 335.424
• Mol File: 895570-99-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2-benzylamino-3-(4-methylsulfonylphenyl)-propane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-benzylamino-3-(4-methylsulfonylphenyl)-propane-1,3-diol(895570-99-7)
• EPA Substance Registry System: (2R,3R)-2-benzylamino-3-(4-methylsulfonylphenyl)-propane-1,3-diol(895570-99-7)

Safety Data

• Hazardous Substances Data: 895570-99-7(Hazardous Substances Data)

Upstream product

• 701935-64-0 1-[4-(methylsulfanyl)phenyl]-2-propen-1-ol 
• 125872-62-0 (E)-3-[4-(methylsulfanyl)phenyl]prop-2-en-1-ol 
• 125872-64-2 (E)-3-[4-(methylsulfonyl)phenyl]prop-2-en-1-ol 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 1338046-00-6 (R)-((R)-3-benzyl-2-oxooxazolidin-4-yl)[4-(methylsulfonyl)phenyl]methyl acetate 
• 1338045-99-0 (R)-3-benzyl-4-[(S)-hydroxy(4-methylsulfonylphenyl)methyl]oxazolidin-2-one 
• 895570-95-3 (4R,5R)-2,3,4,5-tetrahydro-5-(4-methylsulfonylphenyl)-2-oxo-3-benzyl-oxazole-4-methanol 

Downstream Products

• 15318-45-3 thiamphenicol 
• 51458-28-7 (1R,2R)-2-amino-1-<4-(methylsulphonyl)phenyl>-1,3-propanediol 
• 73231-34-2 Florfenicol 
• 143026-79-3 (4S,5R)-2-(dichloromethyl)-4-(fluoromethyl)-5-(4-(methylsulfonyl)phenyl)-4,5-dihydrooxazole 
• 126813-11-4 D-threo-2-(dichloromethyl)-5-(4-methanesulfonylphenyl)-4,5-dihydro-1,3-oxazol-4-yl methanol 

Relevant articles and documents

An efficient enantioselective synthesis of florfenicol via a vanadium-catalyzed asymmetric epoxidation

An efficient and highly enantioselective synthesis of florfenicol 1 was achieved with 37% overall yield starting from commercially available 4-methylthiobenzaldehyde. A key feature of the synthesis is the vanadium-catalyzed asymmetric epoxidation of allylic alcohol 5 with aq tert-butyl hydroperoxide to form (2S,3S)-epoxide 6.