895571-10-5

Basic information

• Product Name: (1R,2S)-1-(4-methylsulfonylphenyl)-2-benzylamino-3-fluoro-1-propanol
• Synonyms: (1R,2S)-1-(4-methylsulfonylphenyl)-2-benzylamino-3-fluoro-1-propanol
• CAS NO: 895571-10-5
• Molecular Weight: 337.415
• Mol File: 895571-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-1-(4-methylsulfonylphenyl)-2-benzylamino-3-fluoro-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-1-(4-methylsulfonylphenyl)-2-benzylamino-3-fluoro-1-propanol(895571-10-5)
• EPA Substance Registry System: (1R,2S)-1-(4-methylsulfonylphenyl)-2-benzylamino-3-fluoro-1-propanol(895571-10-5)

Safety Data

• Hazardous Substances Data: 895571-10-5(Hazardous Substances Data)

Upstream product

• 895571-07-0 (4S,5R)-5-(4-methylsulfonylphenyl)-2-oxo-3-benzyl-4-fluoromethyl-oxazolidine 

Downstream Products

• 73231-34-2 Florfenicol 

Relevant articles and documents

New stereoselective synthesis of thiamphenicol and florfenicol from enantiomerically pure cyanohydrin: a chemo-enzymatic approach

Thiamphenicol and florfenicol have been synthesized stereoselectively from enantiomerically pure 4-methylsulfanyl-mandelonitrile, which was obtained by hydrocyanation reaction of 4-methylsulfanyl-benzaldehyde catalyzed by (R)-hydroxynitrile lyase of Badamu (Prunus communis L. var. dulcis Borkh, almond from Xinjiang, China). It was found to be a highly effective bio-catalyst for this reaction after an extensive screening.