89578-12-1

Basic information

• Product Name: Benzenebutanoic acid, (methylthio)methyl ester
• CAS NO: 89578-12-1
• Molecular Formula: C12H16O2S
• Molecular Weight: 224.324
• Mol File: 89578-12-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, (methylthio)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, (methylthio)methyl ester(89578-12-1)
• EPA Substance Registry System: Benzenebutanoic acid, (methylthio)methyl ester(89578-12-1)

Safety Data

• Hazardous Substances Data: 89578-12-1(Hazardous Substances Data)

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 1821-12-1 4-Phenylbutyric acid 
• 2373-51-5 chloro-methylsulfanyl-methane 

Downstream Products

• 70950-06-0 3'-phenyl-1'-propyl 4-phenylbutyrate 
• 89578-16-5 (methylsulfinyl)methyl 4-phenylbutanoate 

Relevant articles and documents

Synthetic method of methylthiomethyl

The invention provides a synthetic method of methylthiomethyl. The synthetic method comprises the step of carrying out crossed dehydrogenation on a carboxylic acid compound and dimethylsulfoxide in the presence of nitrogen and organic amine, so as to gene

Total Synthesis of a Macrocyclic Pyrrolizidine Alkaloid, (+/-)-Integerrimine, Utilizing an Activable Protecting Group

A new esterification reaction has been developed utilizing a (methylthio)methyl (MTM) group as an activable protecting group of carbocyclic acid.A total synthesis of a 12-membered pyrrolizidine alkaloid, (+/-)-integerrimine (1), has been achieved by applying the above method to formation of the macrocyclic bislactone skeleton.The acid anhydride (16b) of the integerrinecic acid derivative was coupled with lithium alkoxide of retronecine silyl ether (5b) in the presence of DMAP to afford the α,β-unsaturated ester.Oxidation of the MTM group afforded an active (methylsulfonyl)methyl ester (28b), which cyclized to give the macrocyclic bislactone 29.