896-32-2Relevant articles and documents
2,2,2-Triphenylethanol: a Hydrogen-Bonded Tetramer Based upon a Centrosymmetric R44(8) Motif
Ferguson, George,Glidewell, Christopher,Zakaria, Choudhury M.
, p. 928 - 931 (1994)
2,2,2-Triphenylethanol, C20H18O, crystallizes as hydrogen-bonded tetrameric aggregates which are centrosymmetric.The resulting planar O4 ring is almost square with O...O distances of 2.786(2) and 2.822(2) Angstroem; the hydroxyl H atoms are fully ordered,
First selective CYP11B1 inhibitors for the treatment of cortisol-dependent diseases
Hille, Ulrike E.,Zimmer, Christina,Vock, Carsten A.,Hartmann, Rolf W.
supporting information; experimental part, p. 2 - 6 (2011/04/17)
Outgoing from an etomidate-based design concept, we succeeded in the development of a series of highly active and selective inhibitors of CYP11B1, the key enzyme of cortisol biosynthesis, as potential drugs for the treatment of Cushing's syndrome and rela
Fragmentation of 2,2,2-triphenylethoxychlorocarbene: Evidence for ultrafast fragmentation-rearrangement in excited diazirines
Fu, Xiaolin,Moss, Robert A.,Piotrowiak, Piotr,Myahkostupov, Mykhaylo,Gould, Ian R.
, p. 4807 - 4809 (2007/10/03)
(Chemical Equation Presented) Photolysis of 3-(2,2,2-triphenylethoxy)-3- chlorodiazirine gives 2,2,2-triphenylethoxychlorocarbene which fragments with 1,2-phenyl migration and loss of CO and Cl- to yield the 1,1,2-triphenylethyl cation and thence 1,1,2-triphenylethene by proton loss. However, ps and fs laser flash photolysis provides evidence that up to 25% of the alkene product stems from carbocation that arises directly from excited diazirine rather than from the carbene.