89697-78-9 Usage
Uses
Polyhexamethyleneguanidine phosphate (PHMG-P) has been widely used as a disinfectant because of its strong bactericidal activity and low toxicity.
Toxicity evaluation
Administration of PHMG-P induced proinflammatory cytokines elevation and infiltration of immune cells into the lungs. Histopathological analysis revealed a dose-dependent exacerbation of both inflammation and pulmonary fibrosis on day 14. PHMG-P also decreased the total cell number and the CD4+/CD8+ cell ratio in the thymus, with the histopathological examination indicating severe reduction of cortex and medulla. The mRNA levels of biomarkers associated with T cell development also decreased markedly. These findings suggest that exposure of lung tissue to PHMG-P leads to pulmonary inflammation and fibrosis as well as thymic atrophy.
Check Digit Verification of cas no
The CAS Registry Mumber 89697-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,6,9 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 89697-78:
(7*8)+(6*9)+(5*6)+(4*9)+(3*7)+(2*7)+(1*8)=219
219 % 10 = 9
So 89697-78-9 is a valid CAS Registry Number.
89697-78-9Relevant articles and documents
ANTIBACTERIAL MICRO- AND NANOPARTICLES COMPRISING A CHLORHEXIDINE SALT, METHOD OF PRODUCTION AND USES THEREOF
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Page/Page column 26; 27, (2014/12/12)
Antimicrobial micro- or nanoparticles comprising a chlorhexidine salt and an anion, and a method of making the antimicrobial micro-or nanoparticle, are disclosed. The anion in the salt is selected from oxoanions and partially hydrogenated oxoanions of phosphorus, carbon, nitrogen, and sulfur.
