897016-95-4

Basic information

• Product Name: Morpholine, 4-(4-bromo-3-fluorobenzoyl)-
• CAS NO: 897016-95-4
• Molecular Formula: C11H11BrFNO2
• Molecular Weight: 288.116
• Mol File: 897016-95-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(4-bromo-3-fluorobenzoyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(4-bromo-3-fluorobenzoyl)-(897016-95-4)
• EPA Substance Registry System: Morpholine, 4-(4-bromo-3-fluorobenzoyl)-(897016-95-4)

Safety Data

• Hazardous Substances Data: 897016-95-4(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 153556-42-4 4-bromo-3-fluorobenzoic acid 

Downstream Products

• 304445-49-6 1-(4-bromo-3-fluorophenyl)ethan-1-one 
• 1092500-69-0 2-fluoro-4-(morpholine-4-carbonyl)boronic acid 
• 897016-96-5 4-(4-bromo-3-fluorobenzyl)morpholine 

Relevant articles and documents

TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS

A compound of formula I wherein: n is 1 or 2: p is 0 or 1; R1 is optionally one or more halo or methyl groups; R2a and R2b are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R2c and R2d are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH2OH; R3a and R3b are independently selected from H and Me; R4 is either H or Me; R5 is either H or Me; R6a and R6b are independently selected from H and Me; A is either (i) optionally substituted phenyl; (ii) optionally substituted naphthyl; or (iii) optionally substituted C5-12 heteroaryl.

SUBSTITUTED TRIAZOLOPYRIDINES

The present invention relates to substituted triazolopyridine compounds of general formula (I) : in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease of uncontrolled cell growth, proliferation and/or survival as well as to the use of intermediate compounds for the preparation of said compounds.

Compositions and methods of treating cell proliferation disorders

The invention relates to compounds and methods for treating cell proliferation disorders.