897299-71-7

Basic information

• Product Name: C₂₁H₁₇N₃O
• Synonyms: C₂₁H₁₇N₃O
• CAS NO: 897299-71-7
• Molecular Weight: 327.385
• Mol File: 897299-71-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₇N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₇N₃O(897299-71-7)
• EPA Substance Registry System: C₂₁H₁₇N₃O(897299-71-7)

Safety Data

• Hazardous Substances Data: 897299-71-7(Hazardous Substances Data)

Upstream product

• 1026289-65-5 C₂₂H₂₀O₃ 
• 50-01-1 guanidine hydrochloride 

Relevant articles and documents

Direct synthesis of 5- and 6-substituted 2-aminopyrimidines as potential non-natural nucleobase analogues

A series of 2-aminopyrimidine derivatives, substituted at 5- and 6-positions, were synthesized. The reaction was carried out in a single step by treatment of the corresponding β-ketoester or β-aldehydoester with guanidine hydrochloride in the presence of K2CO3, in a microwave-assisted method without the requirement of solvent. A unique 1:1 co-crystal structure was obtained which shows that a 6-phenyl-2- aminopyrimidinone forms a strong nucleobase-pair with cytosine, involving three hydrogen bonds. The base-pair was found to be as strong as that of natural guanine:cytosine (G:C), signifying the potential application of the synthesized derivatives. Additionally, we also report a second co-crystal involving 5-isopropyl-6-methyl-2-aminopyrimidinone and cytosine in a 1:1 ratio, which also shows strong base-pairing properties. the Partner Organisations 2014.