897384-05-3

Basic information

• Product Name: (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide
• Synonyms: (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide
• CAS NO: 897384-05-3
• Molecular Weight: 504.976
• Mol File: 897384-05-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide(897384-05-3)
• EPA Substance Registry System: (2S)-pyrrolidine-2-carboxylic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-7-methoxy-quinazolin-6-yl}-amide(897384-05-3)

Safety Data

• Hazardous Substances Data: 897384-05-3(Hazardous Substances Data)

Upstream product

• 162012-69-3 7-fluoro-6-nitro-3H-quinazolin-4-one 
• 1012057-47-4 7-methoxy-6-nitroquinazolin-4(3H)-one 
• 55496-69-0 4-chloro-7-methoxy-6-nitroquinazoline 
• 1194097-41-0 2-amino-4-fluoro-5-nitrobenzoic acid 
• 897384-03-1 N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-7-methoxy-6-nitroquinazoline-4-amine 

Relevant articles and documents

Synthesis of quinazoline analogues with differential activity for HER2-overexpressing breast cancer cells

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QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF

The present invention relates to a novel quinazoline derivative and a pharmaceutically acceptable salt thereof for inhibiting the growth of cancer cells, a method for the preparation thereof and a pharmaceutical composition comprising same as an active ingredient.