897402-13-0

Basic information

• Product Name: 5-(3-bromophenyl)-5-(7-cyanomethoxy-1H-indole)pentanenitrile
• Synonyms: 5-(3-bromophenyl)-5-(7-cyanomethoxy-1H-indole)pentanenitrile
• CAS NO: 897402-13-0
• Molecular Weight: 408.297
• Mol File: 897402-13-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(3-bromophenyl)-5-(7-cyanomethoxy-1H-indole)pentanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-bromophenyl)-5-(7-cyanomethoxy-1H-indole)pentanenitrile(897402-13-0)
• EPA Substance Registry System: 5-(3-bromophenyl)-5-(7-cyanomethoxy-1H-indole)pentanenitrile(897402-13-0)

Safety Data

• Hazardous Substances Data: 897402-13-0(Hazardous Substances Data)

Upstream product

• 20289-27-4 7-benzyloxyindole 
• 2380-84-9 7-Indolol 
• 135328-50-6 7-(Cyanomethoxy)indole 
• 3132-99-8 m-bromobenzoic aldehyde 
• 135328-49-3 7-(diphenylmethoxy)indole 

Relevant articles and documents

Replacement of Stoichiometric DDQ with a Low Potential o-Quinone Catalyst Enabling Aerobic Dehydrogenation of Tertiary Indolines in Pharmaceutical Intermediates

A transition-metal/quinone complex, [Ru(phd)3]2+ (phd = 1,10-phenanthroline-5,6-dione), is shown to be effective for aerobic dehydrogenation of 3° indolines to the corresponding indoles. The results show how low potential quinones may be tailored to provide a catalytic alternative to stoichiometric DDQ, due to their ability to mediate efficient substrate dehydrogenation while also being compatible with facile reoxidation by O2. The utility of the method is demonstrated in the synthesis of key intermediates to pharmaceutically important molecules.

Process for preparing N-benzyl indoles

A process for producing a compound of the formu5la STR1 comprising the step of reacting a compound of the formula STR2 with a compound of the formula STR3 to form a compound of the formula STR4 wherein R2a is selected from the groups recited ab