89791-34-4

Basic information

• Product Name: Benzamide, N,N'-(thiodi-4,1-phenylene)bis[3,4-diamino-
• CAS NO: 89791-34-4
• Molecular Formula: C26H24N6O2S
• Molecular Weight: 484.582
• Mol File: 89791-34-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N'-(thiodi-4,1-phenylene)bis[3,4-diamino-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N'-(thiodi-4,1-phenylene)bis[3,4-diamino-(89791-34-4)
• EPA Substance Registry System: Benzamide, N,N'-(thiodi-4,1-phenylene)bis[3,4-diamino-(89791-34-4)

Safety Data

• Hazardous Substances Data: 89791-34-4(Hazardous Substances Data)

Upstream product

• 89791-26-4 Bis<4-<(m-nitro-p-acetamidobenzoyl)amino>phenyl> sulfide 
• 556-08-1 p-(acetylamino)benzoic acid 
• 24170-23-8 3-nitro-4-acetylaminobenzoyl chloride 
• 1539-06-6 3-nitro-4-acetamidobenzoic acid 
• 89791-30-0 bis<4-<(m-nitro-p-aminobenzoyl)amino>phenyl> sulfide 

Relevant articles and documents

Syntheses and anthelmintic activity of alkyl 5(6)-(substituted-carbamoyl)- and 5(6)-(disubstituted-carbamoyl)benzimidazole-2-carbamates and related compounds

A number of alkyl 5(6)-(sustituted-carbamoyl)- and 5(6)-(disubstituted-carbamoyl)benzimidazole-2-carbamates and related compounds have been synthesized, and their anthelmintic activity against various intestinal helminths of experimental animals have been evaluated. A large percentage of the compounds synthesized showed noteworthy activity against Ancylostoma ceylanicum and at higher doses against Hymenolepsis nana infections. Compared to the alkyl 5(6)-(substituted-carbamoyl)benzimidazole-2-carbamates, the disubstituted carbamoyl analogues were found to exhibit better anthelmintic activity. The most active compound of the series, namely, methyl 5(6)-[(N-2- pyridylpiperazino)carbamoyl]benzimidazole-2-carbamate (90), has been screened against intestinal helminths in higher animals and as a micro- and macrofilaricidal agent. Compound 90 has been identified as a broad-spectrum anthelmintic agent. Compound 90 has been identified as a broad-spectrum anthelmintic in view of its efficacy against A. ceylanicum (hamsters and dogs), H. nana (rats), Nippostrongylus brasiliensis (rats), Syphacia obvelata (mice), A. tubaeformis (cat), Toxocara spp. (cat), and Litomososoides carinii (cotton rat).