897918-85-3

Basic information

• Product Name: 3-(2-BROMOPHENYL)-3-CHLOROPROPAN-1-OL
• Synonyms: 3-(2-BROMOPHENYL)-3-CHLOROPROPAN-1-OL
• CAS NO: 897918-85-3
• Molecular Formula: C9H10BrClO
• Molecular Weight: 0
• Mol File: 897918-85-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(2-BROMOPHENYL)-3-CHLOROPROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-BROMOPHENYL)-3-CHLOROPROPAN-1-OL(897918-85-3)
• EPA Substance Registry System: 3-(2-BROMOPHENYL)-3-CHLOROPROPAN-1-OL(897918-85-3)

Safety Data

• Hazardous Substances Data: 897918-85-3(Hazardous Substances Data)

Upstream product

• 628-51-3 diacetoxymethane 
• 2039-88-5 2-bromostyrene 
• 75-09-2 dichloromethane 
• 10534-59-5 tetrabutylammonium acetate 

Relevant articles and documents

Boron trifluoride mediated prins reaction of methylene diacetate with styrenes. One-pot synthesis of 3-chloro-3-arylpropanols

A one-pot procedure was developed for the synthesis of 3-chloro-3- arylpropanols, which are important starting materials for the synthesis of biologically active benzanilide derivatives. Styrenes were reacted with methylene diacetate in the presence of boron trifluoride to give the corresponding 3-chloro-3-arylpropanols in 36-84% yield by the Prins reaction. A strongly electron-donating methoxy substituent at either the ortho or para position of the styrene did not give the expected 3-chloro-3-arylpropanols due to polymerization. Styrene with a strongly electron-withdrawing nitro substituent gave the corresponding 3-chloro-3-arylpropanol in very low yield. Under the same reaction conditions, substituted norbornene gave a tricyclic ether. A very easy procedure for the synthesis of methylene diacetate is also reported. Georg Thieme Verlag Stuttgart.