89895-55-6 Usage
Description
METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE is an organic compound that serves as an essential intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its unique chemical structure, which features a piperidine ring with a carboxylate group and a methyl ester, making it a versatile building block in the development of new drugs and chemical entities.
Uses
Used in Pharmaceutical Industry:
METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE is used as a key intermediate in the synthesis of indazole carboxamides, which are known as RIPK1 kinase inhibitors. These inhibitors play a crucial role in regulating cellular processes and have potential therapeutic applications in the treatment of various diseases, including inflammatory and neurodegenerative disorders.
In the preparation of indazole carboxamides, METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE serves as a valuable precursor, allowing chemists to construct the desired molecular structures with specific biological activities. Its reactivity and functional groups enable the formation of new chemical bonds and the introduction of various substituents, which can modulate the potency, selectivity, and pharmacokinetic properties of the resulting compounds.
Furthermore, METHYL PIPERIDINE-3-CARBOXYLATE HYDROCHLORIDE can be employed in other applications within the pharmaceutical industry, such as the development of novel drug candidates, optimization of drug delivery systems, and the design of prodrugs that can be metabolized into active therapeutic agents in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 89895-55-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,8,9 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 89895-55:
(7*8)+(6*9)+(5*8)+(4*9)+(3*5)+(2*5)+(1*5)=216
216 % 10 = 6
So 89895-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H13NO2.ClH/c1-10-7(9)6-3-2-4-8-5-6;/h6,8H,2-5H2,1H3;1H
89895-55-6Relevant articles and documents
SUBSTITUTED (PIPERIDIN-1-YL)ARYL ANALOGUES FOR MODULATING AVILACTIVITY
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Paragraph 0449; 0455, (2020/11/12)
In one aspect, the disclosure relates to compounds useful to regulate, limit, or inhibit the expression of AVIL (advillin), methods of making same, pharmaceutical compositions comprising same, and methods of treating disorders associated with AVIL dysregulation using same. In aspects, the disclosed compounds, compositions and methods are useful for treating disorders or diseases in which the regulation, limitation, or inhibition of the expression of AVIL can be clinically useful, such as, for example, the treatment of cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Chemoenzymatic approach to enantiopure piperidine-based β-amino esters in organic solvents
Liljeblad, Arto,Kavenius, Hanna-Maija,Taehtinen, Petri,Kanerva, Liisa T.
, p. 181 - 191 (2007/10/03)
This research concentrates on the enantioselectivities of lipase-catalysed reactions with methyl esters of 2-piperidylacetic acid and 3-piperidinecarboxylic acid derivatives. N-Acetylated 2-piperidylacetic acid methyl ester displayed good enantioselectivi
