89897-04-1

Basic information

• Product Name: 4-HYDROXY-3-METHYLCYCLOHEXANONE
• Synonyms: 4-HYDROXY-3-METHYLCYCLOHEXANONE;4-hydroxy-3-methylcyclohexan-1-one
• CAS NO: 89897-04-1
• Molecular Formula: C7H12O2
• Molecular Weight: 128.16898
• Mol File: 89897-04-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-HYDROXY-3-METHYLCYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-3-METHYLCYCLOHEXANONE(89897-04-1)
• EPA Substance Registry System: 4-HYDROXY-3-METHYLCYCLOHEXANONE(89897-04-1)

Safety Data

• Hazardous Substances Data: 89897-04-1(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-3-Methylcyclohexanone is a type of organic compound recognized by its distinct, syrupy viscosity and colorless or pale yellow appearance. It is commonly utilized in the synthesis of pharmaceuticals, dyestuffs, and fragrances. This chemical is a cyclic ketone, identifiable by its molecular formula C7H12O2. Its Chemical Abstracts Service (CAS) number is 4437-51-3. Despite its widespread commercial application, there is limited available research on 4-Hydroxy-3-Methylcyclohexanone's physical properties and potential hazards. Therefore, appropriate safety and handling measures must be promptly undertaken when dealing with this compound.

Upstream product

• 98-88-4 benzoyl chloride 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 702-69-2 7-methyl-1,4-dioxa-spiro[4.5]decan-8-one 
• 13944-81-5 7-methyl-1,4-dioxa-spiro[4.5]decan-8-ol 
• 122052-59-9 (1S,2R)-2-bromomethyl-4,4-ethylenedioxycyclohexyl benzoate 
• 122052-44-2 (2R,4aS,8aS)-6,6-ethylenedioxy-2-phenyl-1,3-dioxa-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene 
• 96817-54-8 ethyl (1R,2S)-2-acetoxy-5,5-ethylenedioxycyclohexanecarboxylate 
• 96893-99-1 (1R,2S)-5,5-(Ethylendioxy)-2-hydroxycyclohexancarbonsaeure-ethylester 
• 96894-00-7 (1S,2S)-4,4-ethylenedioxy-2-hydroxymethylcyclohexanol 
• 14160-65-7 ethyl 8-oxo-1,4-dioxaspiro[4.5]decane-7-carboxylate 
• 122090-89-5 (1S,2R)-4,4-ethylenedioxy-2-methylcyclohexanol 

Downstream Products

• 122090-95-3 3-((6R,7R,8S)-8-Hydroxy-6,7-dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl)-propionic acid 
• 122052-46-4 (1'R,2'R,3'R)-3-(6',6'-ethylenedioxy-3'-hydroxy-1',2'-dimethylcyclohexane)propanoic acid 

Relevant articles and documents

A vicarious, one-pot synthesis of benzo- and naphthofurans: Applications to the syntheses of stereumene B and paeoveitols

An interesting albeit unexpected deviation during attempted Tanabe γ-lactone annulation on 4-hydroxycyclohexanones has led to a general, one-pot synthesis of benzofurans and naphtho[2,3–b]furans from readily assembled precursors. The utility of this adaptable methodology has been demonstrated through concise syntheses of natural products, stereumene B, paeoveitol D and (±)-paeoveitol.

Synthesis of Normorphans through an Efficient Intramolecular Carbamoylation of Ketones

An unexpected C-C bond cleavage was observed in trichloroacetamide-tethered ketones under amine treatment and exploited to develop a new synthesis of normophans from 4-amidocyclohexanones. The reaction involves an unprecedented intramolecular haloform-typ

Process for the selective enzymatic hydroxylation of aldehydes and ketones

A process for the selective enzymatic hydroxylation of aldehydes and ketones using chiral anchor-protective groups.