89943-82-8

Basic information

• Product Name: Cicletanine
• Synonyms: Cicletanine;3-(4-Chlorophenyl)-1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol;3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol;Furo[3,4-c]pyridin-7-ol, 3-(4-chlorophenyl)-1,3-dihydro-6-methyl-
• CAS NO: 89943-82-8
• Molecular Formula: C₁₄H₁₂ClNO₂
• Molecular Weight: 261.703580
• Mol File: 89943-82-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 446.3 °C at 760 mmHg
• Flash Point: 223.7 °C
• Appearance: /
• Density: 1.351g/cm³
• Vapor Pressure: 1.4E-08mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: Cicletanine(CAS DataBase Reference)
• NIST Chemistry Reference: Cicletanine(89943-82-8)
• EPA Substance Registry System: Cicletanine(89943-82-8)

Safety Data

• Hazardous Substances Data: 89943-82-8(Hazardous Substances Data)

Usage

Uses

Antihypertensive.

InChI:InChI=1/C14H12ClNO2/c1-8-13(17)12-7-18-14(11(12)6-16-8)9-2-4-10(15)5-3-9/h2-6,14,17H,7H2,1H3

Upstream product

• 133545-64-9 (+)-2,2,8-trimethyl-5-(4-chloro-α-hydroxybenzyl)-pyrido-[4,3-e]-1,3-dioxane 

Downstream Products

• 1207474-18-7 (3R,3aR,6R,6aR)-6-((3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yloxy)carbonyloxy)hexahydrofuro[3,2-b]furan-3-yl 4-(nitrooxy)piperidine-1-carboxylate 
• 1207473-83-3 3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yl (1s,3R,4S)-3,4-bis(nitrooxy)cyclopentanecarboxylate 
• 1207474-13-2 3-(4-Chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yl 3-(nitrooxy)propyl carbonate 
• 1207474-12-1 5,6-Bis(nitrooxy)hexyl 3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-yl carbonate 
• 96908-94-0 1,3-dihydro-3-p.chlorophenyl-4-chloro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridine 

Relevant articles and documents

Separation of isomers of furo (3,4-C) pyridine derivatives

This invention relates to a method for the separation of stereoisomers of 7-hydroxy-furo[3,4-c]pyridine derivatives of the formula STR1 wherein R3, R4 and R6 represent various substitutents, which comprises reacting a fully O-acetylated monosaccharide halogenide with a racemate of the selected 7-hydroxy-furo[3,4-c]pyridine derivative, to form the (+) and (-) (O-acetylated monosaccharide) (furo[3,4-c] pyridine 7-yl derivative) ethers, then separating the (+) and the (-) ethers by selective crystallization, in an hydroalcoholic medium, either of the acetylated forms or of the corresponding desacetylated forms and, finally, working up each of the separated derivatives by the usual routes. The compounds are known pharmaceuticals.

Furo-(3,4-c)-pyridine derivatives and their pharmaceutical use

This invention relates to new 1,3-dihydro-6-methyl-7-hydroxy-furo-(3,4-c)-pyridine derivatives of the general formula STR1 wherein A2)n --, n being an integer of from 1 to 5, or a homocyclic o