90-80-2 Usage
Description
Delta-Gluconolactone, also known as D-glucono-1,5-lactone or D-gluconic acid delta-lactone, is a cyclic ester of D-gluconic acid. It is a non-toxic component of the skin and a natural constituent of many foods, such as honey, fruit juices, wine, and fermented products. It has antioxidant and free radical scavenging effects, and possesses anti-aging and skin-firming properties.
Used in Personal Care Industry:
Delta-Gluconolactone is used as a broad-spectrum preservative in a variety of personal care formulations, such as Geogard(R)Ultra, a synergistic blend with sodium benzoate.
Used in Food Industry:
Delta-Gluconolactone is used as a food additive with the E number E575. It functions as a sequestrant, an acidifier, a curing, pickling, or leavening agent. It is used in products like feta cheese, baked goods, fish products, desserts, and dressings. It has a sweet initial taste and a slightly acidic aftertaste, being less tart/sour than other food acids.
Used in Cosmetics:
Delta-Gluconolactone is used in cosmetics for its anti-acne properties, improving skin hydration due to its water-binding ability, and as a product stabilizer (chelating agent). Some studies indicate potential free-radical scavenging capacities, making it relevant for use in anti-aging, moisturizing, and possibly sun care products.
Used in Cleaning Compounds:
Delta-Gluconolactone is a component of many cleaning compounds due to the sequestering ability of the gluconate radical, which remains active in alkaline solutions.
Used in Dairy Industry:
Delta-Gluconolactone is used in the dairy industry to prevent milkstone.
Used in Breweries:
Delta-Gluconolactone is used in breweries to prevent beerstone.
Used in Textile Printing:
Delta-Gluconolactone serves as a latent acid catalyst for acid colloid resins, particularly in textile printing.
Used in Tofu Production:
Delta-Gluconolactone acts as a coagulant in tofu production.
Used as a Nutritional Supplement:
Delta-Gluconolactone can be used as a nutritional supplement in beverages, such as instant drinks, syrups, ready-to-drink tea and coffee, sports and energy drinks, and waters.
Preparation
Glucono delta-lactone is prepared commercially by the oxidation of glucose with bromine water.
Flammability and Explosibility
Nonflammable
Biochem/physiol Actions
Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.
Purification Methods
Crystallise Dglucono-lactone from ethylene glycol monomethyl ether and dry for 1hour at 110o. It can be freed from other sugars via a column of Celite and charcoal (750g of each, 90 x 7.5cm) which is washed with 0.01N formic acid until the pH of the wash is equal to that of the entering acid. The lactone is applied in H2O and eluted with 0.01N formic acid (7L), then eluted with 7.5% EtOH/0.01N formic acid (8L), then 15% EtOH/0.01N formic acid (8L) which removes pentose and isomaltose (the optical rotation of the eluates are used for sugar detection) and finally elution with aqueous formic acid provides glucolactone which is obtained by evaporating or freeze drying. Its solubility in H2O is 60% and 1% in EtOH. A solution in H2O is slightly acidic, and the lactone dissolves in an equivalent of aqueous NaOH to form sodium D-gluconate [527-07-1] M 218.1, m 2002 0 6o(dec), [ ] D 25 +12o (c 10, H2O), pK2 5 3.6. [cf p 553, Smith & Whelan Biochemical Preparations 10 127 1963, Beilstein 3 IV 1255.]
Check Digit Verification of cas no
The CAS Registry Mumber 90-80-2 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90-80:
(4*9)+(3*0)+(2*8)+(1*0)=52
52 % 10 = 2
So 90-80-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m0/s1
90-80-2Relevant articles and documents
Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4-oxadiazole-2(3H)-thione ligands derived from δ-D-gluconolactone
Espinosa, Andrés Villase?or,Costa, Danilo de Souza,Tunes, Luiza Guimar?es,Monte-Neto, Rubens L. do,Grazul, Richard Michael,de Almeida, Mauro Vieira,Silva, Heveline
, p. 41 - 50 (2020/07/28)
Four gold(I) complexes conceived as anticancer agents were synthesized by reacting [Au(PEt3)Cl] and [Au(PPh3)Cl] with ligands derived from δ-d-gluconolactone. The ligands’ structure was designed to combine desired biological properti
Synthesis of Cu(OH)F microspheres using atmospheric dielectric barrier discharge microplasma: a high-performance non-enzymatic electrochemical sensor
Hu, Zhangmei,Huang, Ke,Jiang, Xue,Wang, Qiang,Yu, Huimin,Zhao, Li,Zhou, Jiaxin
supporting information, p. 18277 - 18281 (2021/10/19)
In this study, Cu(OH)F microspheres suppported on a carbon cloth (Cu(OH)F MS/CC) were rapidly synthesized (at 90 V with 20 min) using an atmospheric dielectric barrier discharge microplasma (DBD). As a multifunctional electrochemical sensor for the detection of glucose (Glu), formaldehyde and hydrogen peroxide, it can accurately detect blood glucose levels in actual serum samples and can determine the contents of formaldehyde and hydrogen peroxide in water samples. Furthermore, it shows good sensitivity and selectivity, which confirmed the feasibility of the Cu(OH)F microsphere electrode for electrochemical sensing. This method was not only rapid and mild (at room temperature and atmospheric pressure) but also provided a promising route for the preparation of nanomaterials for electrochemical sensors.
Efficient improvement in non-enzymatic glucose detection induced by the hollow prism-like NiCo2S4electrocatalyst
Chen, Qiwen,Chen, Xiaojun,Chu, Dandan,Chu, Xue-Qiang,Ge, Danhua,Yan, Li
, p. 15162 - 15169 (2021/11/17)
Hollow prism-like NiCo2S4 materials (NiCo2S4 HNPs) were successfully fabricated by a two-step method. Scanning electron microscopy (SEM), transmission electron microscopy (TEM) and powder X-ray diffraction (XRD) confirmed the morphology and structure of the as-prepared NiCo2S4 nanoprisms. A non-enzymatic sensor based on NiCo2S4 HNPs was constructed with outstanding electrochemical activity towards glucose oxidation in alkaline medium. The sensor showed a rapid response time (~0.1 s), a high sensitivity of 82.9 μA mM-1 cm-2, a wide linear range (0.005-20.2 mM) and a detection limit of 0.8 μM (S/N = 3) with a good selectivity and reproducibility. Additionally, the proposed electrode also confirmed the feasibility in practical blood serum. These results indicate that NiCo2S4/ITO has great potential in the development of non-enzymatic glucose sensor applications.