90004-05-0 Usage
Description
2-(1,3,4-oxadiazol-2-yl)aniline(SALTDATA: FREE) is an organic compound characterized by the presence of an oxadiazole ring fused to an aniline group. This unique structure endows it with specific chemical and biological properties, making it a versatile molecule for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
2-(1,3,4-oxadiazol-2-yl)aniline(SALTDATA: FREE) is used as a key intermediate in the synthesis of Heteroaryl compounds, which are known as ZNF143 inhibitors. These inhibitors play a crucial role in modulating the activity of the ZNF143 protein, a transcription factor involved in various cellular processes. By targeting ZNF143, these Heteroaryl compounds have the potential to treat diseases associated with the dysregulation of this protein, such as cancer and other genetic disorders.
In the synthesis of Heteroaryl compounds, 2-(1,3,4-oxadiazol-2-yl)aniline(SALTDATA: FREE) serves as a building block, providing the necessary oxadiazole moiety that can be further functionalized and combined with other molecular fragments to create the desired ZNF143 inhibitors. This makes it an essential component in the development of novel therapeutic agents targeting this important protein.
Check Digit Verification of cas no
The CAS Registry Mumber 90004-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,0 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 90004-05:
(7*9)+(6*0)+(5*0)+(4*0)+(3*4)+(2*0)+(1*5)=80
80 % 10 = 0
So 90004-05-0 is a valid CAS Registry Number.
90004-05-0Relevant articles and documents
Synthesis and single crystal X-ray structure of 2-(1,3,4-oxadiazol-2-yl) aniline
Souldozi, Ali,?lepokura, Katarzyna,Lis, Tadeusz,Ramazani, Ali
, p. 835 - 840 (2007)
Reaction of 2-aminobenzoic acid with (N-isocyanimino)triphenylphosphorane proceeds smoothly at r. t. to afford 2-(1,3,4-oxadiazol-2-yl)aniline in high yield. The structure of this compound was confirmed by IR, 1H, and 13C NMR spectro
Novel, fast and efficient one-pot sonochemical synthesis of 2-aryl-1,3,4-oxadiazoles
Rouhani, Morteza,Ramazani, Ali,Joo, Sang Woo
, p. 262 - 267 (2013/10/01)
Ultrasound promoted synthesis of 2-aryl-1,3,4-oxadiazoles at ambient temperature is reported. The remarkable features of the new procedure are shorter reaction time, excellent yields, cleaner reaction profile and simple experimental and workup procedure.
1,3,4-Benzotriazepinones. Formation and rearrangement
Scheiner,Frank,Giusti,et al.
, p. 1817 - 1824 (2007/10/02)
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