9001-39-2

Basic information

• Product Name: D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE
• Synonyms: D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE;EC 3.1.3.9;GLUCOSE-6-PHOSPHATASE;glucose-6-phosphatase from rabbit*liver crude;glucose-6-phosphatase from rabbit liver;ANTI-G6PC (CENTER) antibody produced in rabbit;G6Pase;G-6-Pase
• CAS NO: 9001-39-2
• Molecular Weight: 0
• Mol File: 9001-39-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /powder with sucrose
• Storage Temp.: −20°C
• CAS DataBase Reference: D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE(CAS DataBase Reference)
• NIST Chemistry Reference: D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE(9001-39-2)
• EPA Substance Registry System: D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE(9001-39-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 9001-39-2(Hazardous Substances Data)

Usage

Description

D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE, also known as glucose-6-phosphatase, is an enzyme that catalyzes the hydrolysis of glucose-6-phosphate into glucose and inorganic phosphate. It plays a crucial role in the regulation of glucose metabolism and is involved in various metabolic pathways, including glycolysis and gluconeogenesis.
Used in Pharmaceutical Industry:
D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE is used as a target enzyme for glucose 6-phosphatase inhibitory assays, which are essential for evaluating the potential therapeutic effects of natural compounds and extracts on glucose metabolism regulation. This application is particularly relevant in the development of treatments for diabetes and other metabolic disorders.
Used in Research Applications:
D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE is used as a research tool for studying the molecular mechanisms of glucose metabolism and the role of glucose-6-phosphatase in various metabolic pathways. This enzyme is also employed in the development and optimization of glucose 6-phosphatase inhibitory assays, which are crucial for identifying novel therapeutic agents with potential applications in the treatment of diabetes and other glucose metabolism-related disorders.
Used in Glucose 6-Phosphatase Inhibitory Assay of Crude C. anisata Leaf Extracts:
D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE is used as an enzyme in glucose 6-phosphatase inhibitory assays for crude C. anisata leaf extracts. This application helps in evaluating the potential inhibitory effects of these extracts on glucose-6-phosphatase activity, which can provide insights into their therapeutic potential in the management of diabetes and other metabolic disorders.
Used in Glucose 6-Phosphatase Inhibitory Assay of Methanolic Leaf and Bark Extracts of Dolichandrone atrovirens:
D-GLUCOSE-6-PHOSPHATE PHOSPHOHYDROLASE is used as an enzyme in glucose 6-phosphatase inhibitory assays for methanolic leaf and bark extracts of Dolichandrone atrovirens. This application aids in assessing the inhibitory effects of these extracts on glucose-6-phosphatase activity, which can contribute to the discovery of novel therapeutic agents for the treatment of diabetes and related metabolic conditions.

Biochem/physiol Actions

Glucose-6-Phosphatase is crucial for regulating glucose homeostasis during starvation. Deficiency of glucose-6-phosphatase is implicated in glycogen storage disease type I (GSDI).