9002-64-6

Basic information

• Product Name: Parathyroid
• Synonyms: kakerbin;parathyrin;parathyroidsolution;paroidin;pth;PARATHYROID HORMONE, HUMAN (53-84);PARATHYROID POWDER;parathormone
• CAS NO: 9002-64-6
• Molecular Weight: 0
• Mol File: 9002-64-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C
• CAS DataBase Reference: Parathyroid(CAS DataBase Reference)
• NIST Chemistry Reference: Parathyroid(9002-64-6)
• EPA Substance Registry System: Parathyroid(9002-64-6)

Safety Data

• RIDADR: UN 3264 8 / PGIII
• Hazardous Substances Data: 9002-64-6(Hazardous Substances Data)

Usage

Description

Parathyroid, also known as parathyroid hormone (PTH), is a hormone produced by the parathyroid glands. It plays a crucial role in regulating calcium and phosphorus levels in the body, maintaining bone health, and supporting the proper functioning of muscles and nerves.

Uses

Used in Medical Diagnostics:
Parathyroid is used as a diagnostic marker for various medical conditions related to calcium and phosphorus metabolism. The PTH Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay used to determine PTH levels in human embryonic kidney (HEK293) cells, helping in the diagnosis and monitoring of conditions such as hyperparathyroidism, hypoparathyroidism, and osteoporosis.
Used in Research:
Parathyroid hormone is used in research to study the mechanisms of calcium and phosphorus regulation, bone metabolism, and the role of parathyroid glands in maintaining overall health. The PTH EIA kit is a valuable tool for researchers to measure PTH levels in various cell types and experimental conditions, contributing to a better understanding of the hormone's functions and potential therapeutic applications.

Biochem/physiol Actions

Parathyroid hormone (PTH) plays a vital role in regulation calcium homeostasis. It increases bone mass in animals and humans by inhibiting osteoblast apoptosis. PTH has potential applications in preventing fractures in postmenopausal women with osteoporosis. Irregular diurnal patterns of PTH leads to sustained mild hypercalcemia in non dialyzed chronic kidney disease (CKD) patients. PTH, along with other heart failure biomarkers play a vital role in measuring disease severity and prognosis of heart failure with preserved ejection fraction (HFpEF). Variation in PTH leads to osteoporosis in asymptomatic hyperparathyroidism (HPT).