90033-85-5

Basic information

• Product Name: 6-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-2-phenyl-
• Synonyms: 4-oxo-2-phenyl-1,4-dihydro-quinoline-6-carboxylic acid;4-oxo-2-phenyl-1,4-dihydro-6-quinolinecarboxylic acid;2-phenyl-4-quinolone-6-carboxylic acid
• CAS NO: 90033-85-5
• Molecular Formula: C16H11NO3
• Molecular Weight: 265.268
• Mol File: 90033-85-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-2-phenyl-(90033-85-5)
• EPA Substance Registry System: 6-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-2-phenyl-(90033-85-5)

Safety Data

• Hazardous Substances Data: 90033-85-5(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 94-09-7 p-aminoethylbenzoate 
• 90034-84-7 methyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate 
• 308087-90-3 ethyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate 

Downstream Products

• 90033-87-7 isopropyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate 
• 90033-89-9 sodium 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate 
• 308087-90-3 ethyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate 
• 90033-88-8 phenethyl 2-phenyl-4-quinolone-6-carboxylate 

Relevant articles and documents

4(1H)-QUINOLONE DERIVATIVES AND USES THEREOF

Compounds of Formula (I) and methods for treating, delaying, and/or preventing the adverse effects of proliferative diseases, such as cancers including, for example, lung cancer, breast cancer, ovarian cancer, prostate cancer, head cancer, neck cancer, he

4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin

Developing new therapeutic strategies to overcome drug resistance of cancer cells is an ongoing endeavor. From among 2 million chemicals, we identi?ed ethyl 4-oxo-2-phenyl-1,4-dihydroquinoline-6-carboxylate (AS1712) as a low-toxicity inhibitor of lung can

4-quinolone derivatives having anti-inflammatory, anti-allergic, antitussive, expectorant and antithrombotic activity

4-Quinolone derivatives of the present invention are useful for their anti-inflammatory, anti-allergenic, antitussive, expectorant and antithrombotic activity. Pharmaceutical compositions containing said compounds and pharmaceutically acceptable salts thereof and methods of treating humans and animals are described herein.