90057-08-2

Basic information

• Product Name: 6-CHLORO-2-METHOXY-7-DEAZAPURINE
• Synonyms: 4-chloro-2-Methoxy-7H-pyrrolo[2,3-d]pyriMidine;4-Chloro-2-Methoxy-1H-pyrrolo[2,3-d]pyriMidine
• CAS NO: 90057-08-2
• Molecular Formula: C₇H₆ClN₃O
• Molecular Weight: 183.597
• Product Categories: Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides
• Mol File: 90057-08-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 180-185°C
• Boiling Point: 378.6°C at 760 mmHg
• Flash Point: 182.7°C
• Appearance: /
• Density: 1.477g/cm³
• Vapor Pressure: 1.36E-05mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: -20°C Freezer
• PKA: 10.02±0.20(Predicted)
• CAS DataBase Reference: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(90057-08-2)
• EPA Substance Registry System: 6-CHLORO-2-METHOXY-7-DEAZAPURINE(90057-08-2)

Safety Data

• Hazardous Substances Data: 90057-08-2(Hazardous Substances Data)

Usage

Description

6-Chloro-2-methoxy-7-deazapurine, with the CAS number 90057-08-2, is an off-white to pale yellow solid compound that is useful in organic synthesis. It is a derivative of purine, an important class of heterocyclic organic compounds that are key constituents of nucleic acids and play a significant role in various biological processes.

Uses

Used in Organic Synthesis:
6-Chloro-2-methoxy-7-deazapurine is used as a synthetic intermediate in the chemical industry for the production of various organic compounds. Its unique structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-chloro-2-methoxy-7-deazapurine is used as a key intermediate in the synthesis of novel drug candidates. Its chemical properties enable it to be modified and functionalized to create new molecules with potential therapeutic applications.
Used in Agrochemical Industry:
6-Chloro-2-methoxy-7-deazapurine is also utilized in the agrochemical industry as a starting material for the development of new pesticides and plant growth regulators. Its reactivity and structural features make it suitable for the creation of compounds with improved efficacy and selectivity.

InChI:InChI=1/C7H6ClN3O/c1-12-7-10-5(8)4-2-3-9-6(4)11-7/h2-3H,1H3,(H,9,10,11)

Upstream product

• 52133-67-2 ethyl 2-cyano-4,4-diethoxybutyrate 
• 90057-07-1 3,4-dihydro-2-methoxy-4-oxo-7H-pyrrolo<2,3-d>pyrimidine 

Downstream Products

• 148214-62-4 2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 1093800-34-0 C₂HF₃O₂*C₂₃H₂₉ClN₆O₅ 
• 1093799-55-3 C₂₈H₃₇ClN₆O₇ 
• 1092524-63-4 4-chloro-7-(2-ethoxycarbonylethyl)-2-methoxy-7H-pyrrolo[2,3-d]pyrimidine 
• 155532-17-5 7-<2-deoxy-3,5-di-O-(4-toluoyl)-β-D-erythro-pentofuranosyl>-2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 90057-09-3 2,4-dimethoxy-7H-pyrrolo<2,3-d>pyrimidine 
• 96022-80-9 4-Chlor-7-<2-desoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl>-2-methox-7H-pyrrolo<2,3-d>pyrimidin 
• 96022-81-0 4-Chlor-7-<2-desoxy-3,5-di-O-(p-toluoyl)-α-D-erythro-pentofuranosyl>-2-methoxy-7H-pyrrolo<2,3-d>pyrimidin 

Relevant articles and documents

Preparation method for catalyzing pyrimidine cyclic hydroxyl chlorination by tetraethylammonium chloride

The invention discloses a preparation method for catalyzing pyrimidine cyclic hydroxyl chlorination by tetraethylammonium chloride, which comprises the following steps: (1) adding phosphorus oxychloride into a container, adding tetraethylammonium chloride as a catalyst, adding a pyrimidine cyclic hydroxyl compound, and heating to react; (2) preparing an alkali liquor, cooling to 0 DEG C, and slowly dropwise adding an obtained reaction liquid into the alkali liquor for quenching to obtain a target product. The method has the advantages that the provided pyrimidine cyclic hydroxyl chlorination catalysis method is small in environmental pollution, the obtained product is light in color, the catalysis efficiency is high, and the phosphorus oxychloride recovery pressure is small.