9007-58-3

Basic information

• Product Name: ELASTIN
• Synonyms: Elastins;ELASTIN, BOVINE;ELASTIN, BOVINE NECK LIGAMENT;ELASTIN, BOVINE NECK LIGAMENT, ALKALINE EXTRACTED;ELASTIN;ELASTIN, WATER SOLUBLE;Elastin from bovine neck ligament;ELASTIN, SOLUBLE, FROM HUMAN LUNG
• CAS NO: 9007-58-3
• Molecular Formula: C27H48N6O6
• Molecular Weight: 552.70662
• EINECS: 232-701-4
• Product Categories: ECM ProteinsProteins and Derivatives;Cell Signaling Enzymes;Elastin;Matrix Metalloproteinases Products;Structural Proteins;ElastinCytoskeleton and Extracellular Matrix;Extracellular Matrix;Extracellular Matrix Peptides and Proteins;Proteins and Derivatives;cosmectics raw materials
• Mol File: 9007-58-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 916.6°Cat760mmHg
• Flash Point: 508.2°C
• Appearance: /powder
• Density: 1.126g/cm³
• Vapor Pressure: 1.5E-34mmHg at 25°C
• Refractive Index: 1.508
• Storage Temp.: 2-8°C
• Solubility: H2O: soluble
• CAS DataBase Reference: ELASTIN(CAS DataBase Reference)
• NIST Chemistry Reference: ELASTIN(9007-58-3)
• EPA Substance Registry System: ELASTIN(9007-58-3)

Safety Data

• Hazard Codes: B
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 9007-58-3(Hazardous Substances Data)

Usage

Description

Elastin is an extracellular matrix protein encoded by the gene ELN, which is mapped to human chromosome 7q11.23. It is a major protein component of elastic fibers and is synthesized from the precursor protein called tropoelastin. Elastin is present in all vertebrates except for the primitive fish and is majorly composed of glycine, proline, and other hydrophobic residues. Elastin is an insoluble extracellular matrix protein and the core protein of elastic fibers that impart elasticity to skin. It is particularly abundant in elastic cartilage, blood-vessel walls, ligaments, and the heart.

Uses

Used in Cosmetics:
Elastin is used as a surface protective agent for alleviating the effects of dry skin, enhancing skin flexibility, improving skin feel, increasing and improving the tension of the skin, and influencing the formation of tropocollagen fibers when used in combination with soluble collagen. Preparations containing elastin and peptides derived from it are reported to promote wound healing. In such systems, elastin can absorb lipids from the skin, and when applied to scars, increase the structural glycoproteins and elastin available in the scar tissue. Elastin is often used in moisturizing products and those products for aging or mature skin.
Used in Research:
Elastin mouse lung has been used as an extracellular matrix (ECM) protein for coating of plates.
Elastin (hydrolyzed) is a modified form of elastin that has better solubility, making it more convenient for use in cosmetic formulations than regular elastin.

Biochem/physiol Actions

Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.

InChI:InChI=1/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1