90122-46-6

Basic information

• Product Name: Propanoic acid, 2-methyl-, 1-(2-methoxyphenyl)-2-propenyl ester
• CAS NO: 90122-46-6
• Molecular Formula: C14H18O3
• Molecular Weight: 234.29100
• Mol File: 90122-46-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-, 1-(2-methoxyphenyl)-2-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-, 1-(2-methoxyphenyl)-2-propenyl ester(90122-46-6)
• EPA Substance Registry System: Propanoic acid, 2-methyl-, 1-(2-methoxyphenyl)-2-propenyl ester(90122-46-6)

Safety Data

• Hazardous Substances Data: 90122-46-6(Hazardous Substances Data)

Upstream product

• 58824-49-0 1-(2-methoxyphenyl)prop-2-en-1-ol 
• 79-31-2 isobutyric Acid 
• 97-72-3 2-Methylpropionic anhydride 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 91176-34-0 5-(2-methoxyphenyl)-2,2-dimethylpent-4-enoic acid 
• 110949-93-4 5-(2-methoxyphenyl)-2,2-dimethylpent-4-en-1-ol 

Relevant articles and documents

Isothiourea-Catalysed Acylative Kinetic Resolution of Aryl–Alkenyl (sp2vs. sp2) Substituted Secondary Alcohols

The non-enzymatic acylative kinetic resolution of challenging aryl–alkenyl (sp2vs. sp2) substituted secondary alcohols is described, with effective enantiodiscrimination achieved using the isothiourea organocatalyst HyperBTM (1 mol %) and isobutyric anhydride. The kinetic resolution of a wide range of aryl–alkenyl substituted alcohols has been evaluated, with either electron-rich or naphthyl aryl substituents in combination with an unsubstituted vinyl substituent providing the highest selectivity (S=2–1980). The use of this protocol for the gram-scale (2.5 g) kinetic resolution of a model aryl–vinyl (sp2vs. sp2) substituted secondary alcohol is demonstrated, giving access to >1 g of each of the product enantiomers both in 99:1 e.r.

STEREOCONTROLLED CONSTRUCTION OF A SPIRO FUSED BICYCLOOCTANE RING SYSTEM BY THE INTRAMOLECULAR DOUBLE MICHAEL REACTION

The lithium enolate from the cyclohexenone (8) possessing the α,β-unsaturated ester moiety caused an intramolecular double Michael reaction to produce stereoselectively the spiro fused bicyclo-octane (10).