90176-80-0 Usage
Description
4-Fluoro-2-(trifluoromethyl)benzaldehyde is an organic compound characterized by the presence of a fluorine atom at the 4-position and a trifluoromethyl group at the 2-position on a benzene ring. It is a key intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structural features and reactivity.
Uses
Used in Pharmaceutical Industry:
4-Fluoro-2-(trifluoromethyl)benzaldehyde is used as a starting material for the synthesis of Fevipiprant, a drug used in the treatment of asthma and allergic diseases. Its unique structure contributes to the drug's therapeutic properties.
Additionally, 4-Fluoro-2-(trifluoromethyl)benzaldehyde is used as a reagent in the preparation of numerous inhibitors targeting proteins such as CRTH2, DP2 Receptor, and Hepatitis B Virus (HBV) Capsid. These inhibitors have potential applications in treating various diseases and conditions by modulating the activity of these proteins.
Used in Agrochemical Industry:
4-Fluoro-2-(trifluoromethyl)benzaldehyde also serves as a key intermediate in the development of agrochemicals, specifically in the synthesis of pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and unwanted plant growth, contributing to improved crop yields and agricultural productivity.
Check Digit Verification of cas no
The CAS Registry Mumber 90176-80-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,1,7 and 6 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 90176-80:
(7*9)+(6*0)+(5*1)+(4*7)+(3*6)+(2*8)+(1*0)=130
130 % 10 = 0
So 90176-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F4O/c9-6-2-1-5(4-13)7(3-6)8(10,11)12/h1-4H
90176-80-0Relevant articles and documents
Flow Chemistry on Multigram Scale: Continuous Synthesis of Boronic Acids within 1 s
Hafner, Andreas,Meisenbach, Mark,Sedelmeier, Joerg
supporting information, p. 3630 - 3633 (2016/08/16)
The benefits and limitations of a simple continuous flow setup for handling and performing of organolithium chemistry on the multigram scale is described. The developed metalation platform embodies a valuable complement to existing methodologies, as it combines the benefits of Flash Chemistry (chemical synthesis on a time scale of 1 s) with remarkable throughput (g/min) while mitigating the risk of blockages.