90213-73-3

Basic information

• Product Name: 2-Amino-4-chlor-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin
• Synonyms: 2-Amino-4-chlor-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin
• CAS NO: 90213-73-3
• Molecular Weight: 571.076
• Mol File: 90213-73-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Amino-4-chlor-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-chlor-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin(90213-73-3)
• EPA Substance Registry System: 2-Amino-4-chlor-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-7H-pyrrolo<2,3-d>pyrimidin(90213-73-3)

Safety Data

• Hazardous Substances Data: 90213-73-3(Hazardous Substances Data)

Upstream product

• 70613-79-5 2,3,5-tri-O-benzyl-D-arabinofuranosyl bromide 
• 70384-51-9 Tris(3,6-dioxaheptyl)amine 
• 52522-49-3 2,3,5-tri-O-benzyl-1-(4-nitrobenzoyloxy)-D-arabinofuranose 
• 84955-31-7 4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 

Relevant articles and documents

NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYERMASE

The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.