90263-74-4Relevant articles and documents
Synthesis of a Monocyclic β-Lactam Stereospecifically Labelled at C-4
Gani, David,Young, Douglas W.,Carr, David M.,Poyser, J. Philip,Sadler, Ian H.
, p. 2811 - 2814 (2007/10/02)
In connection with biosynthetic studies, the β-lactams (5; 4-HR = 2H) and (5; 3-H = 4-HS = 2H) have been synthesized.The 1H and 2H n.m.r. spectra of these compounds confirm the assignment of the stereochemistry to the two hydrogens at C-4 of monocyclic β-lactams such as nocardicin A.Samples of the amino-acid L-asparagine stereospecifically labelled at C-3 have been made in the course of this work.