902637-62-1 Usage
Class
Thiourea class of organic compounds
Structure
a. Allyl group attached to thiourea functional group
b. Thiourea functional group substituted with a 4-butylphenyl group
Medicine and pharmacology
Development of drugs and pharmaceuticals
b. Study of structure and function of proteins and enzymes
c. Potential applications in other industries
Functional groups
Allyl, thiourea, and 4-butylphenyl groups
Chemical properties
a. Reactivity with other compounds due to the presence of thiourea functional group
b. Potential for forming hydrogen bonds due to the presence of nitrogen atoms
Appearance
Likely a solid or crystalline structure based on molecular size and complexity
Solubility
May be soluble in organic solvents such as ethanol or methanol, depending on the specific compound
Potential hazards
May be toxic or harmful if ingested, inhaled, or absorbed through the skin
Precautions
Proper handling, storage, and disposal are necessary to minimize exposure and potential health risks
Methods
Chemical synthesis involving the formation of the thiourea functional group and subsequent attachment of the allyl and 4-butylphenyl groups
Reagents
Various reagents may be used in the synthesis process, depending on the specific method employed
Importance
High purity is essential for applications in medicine and pharmacology to ensure the compound's effectiveness and safety
Techniques
Purification methods such as recrystallization or chromatography may be used to obtain a high-purity product
Check Digit Verification of cas no
The CAS Registry Mumber 902637-62-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,2,6,3 and 7 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 902637-62:
(8*9)+(7*0)+(6*2)+(5*6)+(4*3)+(3*7)+(2*6)+(1*2)=161
161 % 10 = 1
So 902637-62-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H20N2S/c1-3-5-6-12-7-9-13(10-8-12)16-14(17)15-11-4-2/h4,7-10H,2-3,5-6,11H2,1H3,(H2,15,16,17)
902637-62-1Relevant articles and documents
Synthesis and biological evaluation of arylthiourea derivatives with antitubercular activity
Luo, Rusong,Laitinen, Tuomo,Teng, Liyan,Nevalainen, Tapio,Lahtela-Kakkonen, Maija,Zheng, Baofu,Wang, Honghai,Poso, Antti,Zhang, Xuelian
, p. 640 - 650 (2013/08/23)
Tuberculosis (TB) is a contagious disease caused by Mycobacterium tuberculosis (M. tuberculosis), and remains one of the most life-threatening plagues for public health in the world. The emergence of drug resistant strains of TB and co-infection with HIV has further complicated TB treatment. Here, the synthesis and characterizaton of a series of compounds were described, and these were followed by evaluating for their antibacterial activity against M. tuberculosis. Several novel arylthiourea derivatives exhibited excellent activity (lowest MIC=0.09 μg/ml) against M. tuberculosis including drug resistant strains of M. tuberculosis. The results suggest that these compounds are promising candidates for new anti-TB agent development.
