9030-21-1

Basic information

• Product Name: NUCLEOSIDE PHOSPHORYLASE
• Synonyms: Nucleoside Phosphorylase bacterial,PNP, Purine nucleoside phosphorylase, Purine nucleoside:orthophosphate ribosyltransferase;Purine nucleoside phosphorylase [ >=200 units/mg];Deoxyribonucleoside phosphorylase;Purine deoxynucleoside phosphorylase;Purine deoxyribonucleoside phosphorylase;Purine ribonucleoside phosphorylase;PNP/Purine-nucleoside phosphorylase;Purine-nucleoside phosp
• CAS NO: 9030-21-1
• Molecular Formula: C10H12N4O4
• Molecular Weight: 252.22668
• EINECS: 232-857-3
• Mol File: 9030-21-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 591.6°Cat760mmHg
• Flash Point: 311.6°C
• Appearance: /lyophilized powder
• Density: 1.91g/cm³
• Storage Temp.: −20°C
• CAS DataBase Reference: NUCLEOSIDE PHOSPHORYLASE(CAS DataBase Reference)
• NIST Chemistry Reference: NUCLEOSIDE PHOSPHORYLASE(9030-21-1)
• EPA Substance Registry System: NUCLEOSIDE PHOSPHORYLASE(9030-21-1)

Safety Data

• Hazard Codes: B
• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 9030-21-1(Hazardous Substances Data)

Usage

Chemical Properties

Powder

Uses

Nucleoside Phosphorylase from microorganisms has been used: in phosphopentomutase assay for adenosine synthesis for the conversion of 7-methylthioguanosine to 7-methylthioguanine in the synthesis of cytokinins in lyophilized cotton plant samples

General Description

Nucleoside Phosphorylase are trimeric and have a molecular mass of about 100 kDa. Each monomer consists of a mixed β-sheet core flanked by eight α-helices and a purine binding in hydrophobic pocket.

Biochem/physiol Actions

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency.