90358-00-2

Basic information

• Product Name: Dibenzyl(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)phosphat
• Synonyms: Dibenzyl(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)phosphat
• CAS NO: 90358-00-2
• Molecular Weight: 800.885
• Mol File: 90358-00-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Dibenzyl(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)phosphat(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenzyl(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)phosphat(90358-00-2)
• EPA Substance Registry System: Dibenzyl(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)phosphat(90358-00-2)

Safety Data

• Hazardous Substances Data: 90358-00-2(Hazardous Substances Data)

Upstream product

• 90358-01-3 2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl trichloroacetimidate 
• 1623-08-1 phosphoric acid dibenzyl ester 
• 6386-24-9 2,3,4,6-tetra-O-benzyl-D-galactopyranose 
• 90373-52-7 Dibenzyl(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)phosphat 
• 3866-62-4 2,3,4,6-tetra-O-benzyl-1-O-acetyl-α-D-mannopyranose 
• 250691-64-6 2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl iodide 
• 4132-28-9 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside 
• 74808-09-6 2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl trichloroacetimidate 
• 990-91-0 dibenzyl [[bis(benzyloxy)phosphoryl]oxy]phosphonate 
• 6564-72-3 2,3,4,6-tetra-O-benzyl-D-glucopyranose 
• 123417-05-0 dibenzyl phosphorofluoridate 

Relevant articles and documents

Chemical Synthesis of d -glycero- d -manno-Heptose 1,7-Bisphosphate and Evaluation of Its Ability to Modulate NF-κB Activation

D-glycero-d-manno-Heptose 1,7-bisphosphate (HBP) is the precursor for heptose residues found in Gram-negative bacterial membrane surface glycoproteins and glycolipids. HBP β-anomer was recently reported to be a pathogen-associated molecular pattern (PAMP) that regulates TIFA-dependent immunity. Herein, we report the chemical synthesis of HBP α- and β-anomers, which highlights a C-7 carbon homologation via the Corey-Chaykovsky reaction, and the introduction of a phosphate group at the anomeric position using the Mitsunobu reaction. Furthermore, NF-κB reporter assaying revealed that HBP β-anomer activates the NF-κB signaling pathway.

DIBENZYL PHOSPHORFLUORIDATE, A NEW PHOSPHORYLATING AGENT

The first synthesis of dibenzyl phosphorofluoridate and its utility as a phosphorylating agent are described.