903638-15-3

Basic information

• Product Name: C₁₄H₂₀N₂O₄
• CAS NO: 903638-15-3
• Molecular Weight: 280.324
• Mol File: 903638-15-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₂₀N₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₂₀N₂O₄(903638-15-3)
• EPA Substance Registry System: C₁₄H₂₀N₂O₄(903638-15-3)

Safety Data

• Hazardous Substances Data: 903638-15-3(Hazardous Substances Data)

Upstream product

• 109-52-4 valeric acid 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 
• 38291-82-6 valeric acid hydrazide 

Relevant articles and documents

Rational design of inhibitors of VirA-VirG two-component signal transduction

VirA-VirG two-component system regulates the vir (virulence) operon in response to specific host factors (xenognosins) in the plant pathogen Agrobacterium tumefaciens. Using whole cell assays, stable inhibitors inspired by the labile natural benzoxazinone inhibitor HDMBOA are developed. It is found that aromatic aldehydes represent a minimal structural unit for activity. In particular, 3-hydroxy-4,6-dimethoxy-3H-isobenzofuran-1-one (HDI) was found to have the highest activity, making it the most potent developed inhibitor of virulence gene expression in Agrobacterium.