9038-94-2

Basic information

• Product Name: METALLOTHIONEIN
• Synonyms: metallothionein from rabbit liver;METALLOTHIONEIN (MT);Metallothionein from equine kidney;METALLOTHIONEIN;metallothionein from horse kidney
• CAS NO: 9038-94-2
• Molecular Weight: 0
• Product Categories: Sulphur Derivatives
• Mol File: 9038-94-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METALLOTHIONEIN(CAS DataBase Reference)
• NIST Chemistry Reference: METALLOTHIONEIN(9038-94-2)
• EPA Substance Registry System: METALLOTHIONEIN(9038-94-2)

Safety Data

• Hazard Codes: T
• Statements: 45-20/21/22
• Safety Statements: 53-36/37-45
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 9038-94-2(Hazardous Substances Data)

Usage

Description

Metallothionein is an inducible protein that plays a crucial role in the detoxification of heavy metals. It is an intracellular, cytosolic, low-molecular-weight metal-binding protein that consists of two similar low-molecular-weight moieties and has a high cysteine content.

Uses

Used in Pharmaceutical Industry:
Metallothionein is used as a detoxifying agent for heavy metals, particularly in cases of heavy metal poisoning or exposure. Its high affinity for metal ions allows it to bind and sequester toxic heavy metals, reducing their harmful effects on the body.
Used in Environmental Remediation:
Metallothionein can be employed in environmental remediation efforts to remove heavy metals from contaminated sites. Its metal-binding properties make it a promising candidate for the bioremediation of heavy metal-contaminated soils and water sources.
Used in Research:
Metallothionein is also used in research settings to study the mechanisms of heavy metal detoxification and the role of metallothionein in metal homeostasis. This can help in understanding the molecular basis of heavy metal toxicity and developing new therapeutic strategies for heavy metal poisoning.

Purification Methods

Purify it by precipitation to give Zn-and Cd-containing protein fractions and running it on a Sephadex G-75 column, then isoelectric focusing to give two protein peaks [Nordberg et al. Biochem J 126 491 1972, Comeau et al. Prep Biochem 22 151 1992].