90390-12-8 Usage
Description
N-Ethyl-4-(trifluoromethyl)benzylamine is an organic compound with the chemical formula C10H12F3N. It is a derivative of benzylamine, featuring an ethyl group and a trifluoromethyl group attached to the benzene ring. N-Ethyl-4-(trifluoromethyl)benzylamine is known for its potential applications in various fields, particularly in the synthesis of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
N-Ethyl-4-(trifluoromethyl)benzylamine is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure, including the trifluoromethyl group, can impart specific properties to the final drug molecules, such as increased lipophilicity, metabolic stability, and binding affinity to target proteins.
Used in Agrochemical Industry:
N-Ethyl-4-(trifluoromethyl)benzylamine is used in the preparation of 1,2-dithiolone compounds. These compounds have demonstrated potential as effective agents for controlling phytopathogenic microorganisms. By incorporating this compound into the synthesis of 1,2-dithiolone derivatives, it can contribute to the development of new and improved agrochemicals for managing plant diseases and protecting crop yields.
Check Digit Verification of cas no
The CAS Registry Mumber 90390-12-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,3,9 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 90390-12:
(7*9)+(6*0)+(5*3)+(4*9)+(3*0)+(2*1)+(1*2)=118
118 % 10 = 8
So 90390-12-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12F3N/c1-2-14-7-8-3-5-9(6-4-8)10(11,12)13/h3-6,14H,2,7H2,1H3
90390-12-8Relevant articles and documents
Deoxygenative hydroboration of primary, secondary, and tertiary amides: Catalyst-free synthesis of various substituted amines
An, Duk Keun,Jaladi, Ashok Kumar,Kim, Hyun Tae,Yi, Jaeeun
, (2021/11/17)
Transformation of relatively less reactive functional groups under catalyst-free conditions is an interesting aspect and requires a typical protocol. Herein, we report the synthesis of various primary, secondary, and tertiary amines through hydroboration of amides using pinacolborane under catalyst-free and solvent-free conditions. The deoxygenative hydroboration of primary and secondary amides proceeded with excellent conversions. The comparatively less reactive tertiary amides were also converted to the corresponding N,N-diamines in moderate yields under catalyst-free conditions, although alcohols were obtained as a minor product.
A PHARMACEUTICAL COMPOSITION COMPRISING A SUBSTITUTED PHENYLPROPIONIC ACID AS A FREE ACID AND AS TERT-BUTYL AMINE SALT THEREOF
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Page/Page column 35, (2008/06/13)
A pharmaceutical composition comprising a compound of formula I wherein n is 1 or 2, R1 represents hydrogen, chloro, trifluoromethyl or trifluoromethoxy, R2 represents hydrogen or fluoro and R3 represents a C2-6alkyl group, wherein the compound of formula (I) is present in the composition as a free acid and as a tert-butyl amine salt thereof.
ORTHO-SUBSTITUTED BENZOIC ACID DERIVATIVES FOR THE TREATMENT OF INSULIN RESISTANCE
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Page 34, (2008/06/13)
The present invention provides a compound of formula (I), wherein n is 0, 1 or 2; R1 represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substitu
