904318-52-1

Basic information

• Product Name: (E)-3-(dimethylamino)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one
• Synonyms: (E)-3-(dimethylamino)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one
• CAS NO: 904318-52-1
• Molecular Weight: 209.22
• Mol File: 904318-52-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-3-(dimethylamino)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(dimethylamino)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one(904318-52-1)
• EPA Substance Registry System: (E)-3-(dimethylamino)-1-(5-fluoro-2-hydroxyphenyl)prop-2-en-1-one(904318-52-1)

Safety Data

• Hazardous Substances Data: 904318-52-1(Hazardous Substances Data)

Upstream product

• 69155-76-6 6-fluorochromone-3-carboxaldehyde 
• 124-40-3 dimethyl amine 
• 394-32-1 1-(5-fluoro-2-hydroxyphenyl)ethan-1-one 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 1017080-47-5 6-fluoro-3-(p-tolyl)-4H-chromen-4-one 
• 454689-23-7 6-fluoro-3-iodo-4H-1-benzopyran-4-one 

Relevant articles and documents

Visible-light-driven, radical-triggered tandem cyclization of o-hydroxyaryl enaminones: Facile access to 3-CF2/CF3-containing chromones

A practical and straightforward synthetic route to construct a variety of 3-CF2/CF3-containing chromones via photoredox catalysis was developed. This novel protocol features a visible-light-induced radical-triggered tandem cyclizatio

A facile and general approach to 3-((trifluoromethyl)thio)-4 H -chromen-4-one

A facile and efficient synthetic strategy to 3-((trifluoromethyl)thio)-4H-chromen-4-one was developed. AgSCF3 and trichloroisocyanuric acid were employed here to generate active electrophilic trifluoromethylthio species in situ. This reaction could proceed under mild conditions in a short reaction time and be insensitive to air and moisture.