904320-55-4

Basic information

• Product Name: 3-cyano-1-methoxycarbonylindole
• Synonyms: 3-cyano-1-methoxycarbonylindole
• CAS NO: 904320-55-4
• Molecular Formula: C11H8N2O2
• Molecular Weight: 200
• Mol File: 904320-55-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-cyano-1-methoxycarbonylindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyano-1-methoxycarbonylindole(904320-55-4)
• EPA Substance Registry System: 3-cyano-1-methoxycarbonylindole(904320-55-4)

Safety Data

• Hazardous Substances Data: 904320-55-4(Hazardous Substances Data)

Upstream product

• 5457-28-3 3-cyano-1H-indole 
• 79-22-1 methyl chloroformate 

Relevant articles and documents

Hydroheteroarylation of alkynes under mild nickel catalysis

Nickel complexes having a bulky tri(sec-alkyl)phosphine ligand catalyze hydroheteroarylation of alkynes at 35 °C. Selective activation of an Ar-H bond over an Ar-CN bond of N-protected 3-cyanoindoles is achieved by a proper choice of ligand and/or an N-protecting group. The catalysis is applicable to a diverse range of heteroarenes to afford cis-hydroheteroarylation products in highly chemo- and stereoselective manners. Excellent regioselectivity is observed with unsymmetrical alkynes to give the corresponding heteroaryl-substituted ethenes having a larger substituent trans to an aryl group. Copyright