90470-72-7

Basic information

• Product Name: Benzene, 1-(dimethoxymethyl)-3-methyl-
• CAS NO: 90470-72-7
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol File: 90470-72-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(dimethoxymethyl)-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(dimethoxymethyl)-3-methyl-(90470-72-7)
• EPA Substance Registry System: Benzene, 1-(dimethoxymethyl)-3-methyl-(90470-72-7)

Safety Data

• Hazardous Substances Data: 90470-72-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 108-38-3 m-xylene 
• 100-80-1 3-methylstyrene 
• 620-23-5 m-tolyl aldehyde 
• 149-73-5 trimethyl orthoformate 
• 587-04-2 m-Chlorobenzaldehyde 
• 3395-80-0 1,1-dimethoxy-1-(3-chlorophenyl)methane 
• 74-88-4 methyl iodide 

Downstream Products

• 15728-26-4 2-(3-methylbenzylidene)malononitrile 
• 620-23-5 m-tolyl aldehyde 
• 1435943-19-3 methyl 4-(3-methylphenyl)-5-cyano-2-hydroxy-6-phenyl-3,4-dihydro-2H-pyran-2-carboxylate 
• 1148004-81-2 (E)-methyl 2-oxo-4-(m-tolyl)but-3-enoate 
• 1374030-81-5 C₁₇H₁₆O 
• 1374030-62-2 C₁₇H₁₈O₂ 
• 90470-71-6 1-methoxy-1-(3-methylphenyl)acetonitrile 
• 147678-08-8 1-phenyl-1-(3-methylphenyl)methyl methyl ether 

Relevant articles and documents

MOF-808 as a recyclable catalyst for the photothermal acetalization of aromatic aldehydes

Metal-organic frameworks (MOFs) show promise for catalysis applications due to their porosity, high internal surface area, and structural adaptability. Typical acetylation reactions of aldehydes require elevated temperatures and excess alcohol to drive the reactions to completion. In this current work, MOF-808 is used as a heterogeneous catalyst for acetylation of aldehydes in methanol using a mild photothermal process. Optimized conditions gave 72% yield of 2-(dimethoxymethyl)naphthalene in the presence of 10 mol% MOF-808 at 45 °C using only a fluorescent lamp. MOF-808 can be recycled up to 5 times with no loss in catalytic activity. A proof-of-principle substrate scope demonstrates the potential utility for aromatic and aliphatic substrates.

House bulb light-induced photochemical acetalization of carbonyl compounds catalyzed by Eosin Y

We have systematically studied the reactions of acetalization and found that high reaction efficiency can be achieved using cheap and readily available organic Eosin Y as catalyst. The reaction proceeds smoothly under house bulbs and shows excellent functional group tolerance. The substrates of the reaction system are compatible with aromatic aldehydes, aliphatic aldehydes, aromatic ketones, and cyclic ketones with high yields.

Synthesis of unnatural α-amino esters using ethyl nitroacetate and condensation or cycloaddition reactions

We report here on the use of ethyl nitroacetate as a glycine template to produce α-amino esters. This started with a study of its condensation with various arylacetals to give ethyl 3-aryl-2-nitroacrylates followed by a reduction (NaBH4 and then zinc/HCl) into α-amino esters. The scope of this method was explored as well as an alternative with arylacylals instead. We also focused on various [2 + 3] cycloadditions, one leading to a spiroacetal, which led to the undesired ethyl 5-(benzamidomethyl)isoxazole-3-carboxylate. The addition of ethyl nitroacetate on a 5-methylene-4,5-dihydrooxazole using cerium(IV) ammonium nitrate was also explored and the synthesis of other oxazole-bearing α-amino esters was achieved using gold(I) chemistry.