90473-01-1 Usage
Description
(+)-(1R,2R,5R)--Ethyl [(2-Hydroxypinan-3-ylene)aMino]acetate is a chiral compound with a unique molecular structure, characterized by its specific stereochemistry (1R,2R,5R). It is a derivative of (+)-(1R,2R,5R)-2-Hydroxy-3-pinanone (H952000) and serves as an intermediate in the synthesis of D-erythro-Sphingosine (S681000). This clear liquid possesses distinct chemical properties that make it valuable in various applications.
Uses
Used in Pharmaceutical Industry:
(+)-(1R,2R,5R)--Ethyl [(2-Hydroxypinan-3-ylene)aMino]acetate is used as an intermediate in the synthesis of D-erythro-Sphingosine (S681000) for its potential therapeutic applications. D-erythro-Sphingosine has been studied for its role in cell signaling and membrane stability, making it a promising candidate for the development of drugs targeting various diseases.
Used in Chemical Synthesis:
(+)-(1R,2R,5R)--Ethyl [(2-Hydroxypinan-3-ylene)aMino]acetate is used as a chiral building block in the synthesis of other complex organic compounds. Its unique stereochemistry allows for the creation of enantiomerically pure products, which is crucial in many chemical and pharmaceutical applications where the stereochemistry of a molecule can significantly impact its biological activity.
Used in Research and Development:
(+)-(1R,2R,5R)--Ethyl [(2-Hydroxypinan-3-ylene)aMino]acetate is utilized in research settings to study the effects of stereochemistry on the properties and reactivity of molecules. Its clear liquid form and distinct chemical properties make it an ideal candidate for investigations into asymmetric synthesis, chiral recognition, and the development of new methodologies for the preparation of enantiomerically pure compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 90473-01-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,4,7 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 90473-01:
(7*9)+(6*0)+(5*4)+(4*7)+(3*3)+(2*0)+(1*1)=121
121 % 10 = 1
So 90473-01-1 is a valid CAS Registry Number.
90473-01-1Relevant articles and documents
NOVEL SYNTHESIS INTERMEDIATES FOR OBTAINING DERIVATIVES OF SPHINGOSINES, CERAMIDES AND SPHINGOMYELINS WITH GOOD YIELDS
-
, (2016/04/19)
The subject matter of the present invention is the novel molecules of formulae E, E′ and F. These molecules prove to be synthesis intermediates that are very advantageous for the manufacture of derivatives of sphingosine or of ceramides functionalized in position 1, with good yields, in which R1 and R2 are fatty chains, R3 is an alkyl group and R4 is a protective group for alcohol functions. Another subject of the invention is the use of the intermediates of type F for converting same into intermediates of type G, by means of reduction in the presence of lithium borohydride. The G molecules are precursors that are known to make it possible to obtain sphingolipids or sphingomyelin.
A four-step synthesis of erythro-m-chloro-3-hydroxytyrosine ethyl ester enantiomerically pure
Solladie-Cavallo, Arlette,Nsenda, Thomas
, p. 2191 - 2194 (2007/10/03)
Pure erythro-m-chloro-3-hydroxytyrosine having the (2R,3R) configuration, a residue of Vancomycin and Aridicin A, has been prepared in 4 steps using an aldol addition involving a directly generated titanium enolate derived from a chiral iminoglycinate. (+)-Hydroxypinanone was used as a recoverable chiral auxiliary. The (2S,3S)-erythro isomer will be, of course, available from (-)-hydroxypinanone.
