904893-22-7

Basic information

• Product Name: (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide
• Synonyms: (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide
• CAS NO: 904893-22-7
• Molecular Weight: 417.505
• Mol File: 904893-22-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide(904893-22-7)
• EPA Substance Registry System: (2S,3S,4S)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)-3,4-dihydro-2H-pyrrole-1-oxide(904893-22-7)

Safety Data

• Hazardous Substances Data: 904893-22-7(Hazardous Substances Data)

Upstream product

• 201290-06-4 3,4,6-tri-O-benzyl-1,2-dideoxy-D-xylo-hex-1-enitol 
• 16838-89-4 2,3,5-tri-O-benzyl-D-xylofuranose 
• 904893-23-8 (3S,4R,5R)-5-methanesulfonyloxy-3,4,6-tribenzyloxy-1-hexene 
• 913365-64-7 (2S,3S,4S)-2,3,5-Tris-benzyloxy-4-hydroxy-pentanal oxime 
• 96192-07-3 2,3,5-tri-O-benzyl-L-arabinofuranose 
• 913365-65-8 C₃₂H₄₂INO₄Si 
• 904893-24-9 (-)-(2R,3R,4R)-1,3,4-tris(benzyloxy)-5-oxopentan-2-yl methanesulfonate 

Downstream Products

• 52019-89-3 (2S,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol 

Relevant articles and documents

Small structure tree alkali compound and its preparation method and application

The invention relates to a Broussonetia kazinoki alkaline compound. Structure of the compound is shown as a formula (1). The invention further provides a preparation method of the compound, a glycosidase inhibitor by using the compound or the compound prepared by the method as an active ingredient and application of the compound or the compound, prepared by the method, serving as an active ingredient in preparing drug. The Broussonetia kazinoki alkaline compound has high glycosidase inhibiting activity and potential medicinal value.

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpe

Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library

Inspired by polyhydroxylated pyrrolidine alkaloid natural products, a 18-membered library of 2-aryl polyhydroxylated pyrrolidines has been efficiently prepared in two or three synthetic steps from the known chiral cyclic nitrones with high yield and purity and excellent stereoselectivity. The inhibitory activity of all these compounds against various glycosidase enzymes was evaluated. Interestingly, 15 and 19 show better inhibitory activities than radicamine A (20) and B (18) against α-glucosidases. The IC50 values of 15 and 19 are 1.1 and 0.5 μM, respectively. In this study, we also discovered the substituent(s) on the aryl ring could affect the inhibition potency and selectivity against glycosidases.