90490-63-4

Basic information

• Product Name: Ethanone, 1-(4-methylphenyl)-2-(1H-pyrrol-1-yl)-
• CAS NO: 90490-63-4
• Molecular Formula: C13H13NO
• Molecular Weight: 199.252
• Mol File: 90490-63-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(4-methylphenyl)-2-(1H-pyrrol-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-methylphenyl)-2-(1H-pyrrol-1-yl)-(90490-63-4)
• EPA Substance Registry System: Ethanone, 1-(4-methylphenyl)-2-(1H-pyrrol-1-yl)-(90490-63-4)

Safety Data

• Hazardous Substances Data: 90490-63-4(Hazardous Substances Data)

Upstream product

• 109-97-7 pyrrole 
• 619-41-0 4-(bromoacetyl)toluene 
• 124337-35-5 1-Pyrrol-1-ylmethyl-1H-benzotriazole 
• 104-87-0 4-methyl-benzaldehyde 
• 124337-62-8 2-Benzotriazol-1-yl-2-pyrrol-1-yl-1-p-tolyl-ethanol 
• 124337-57-1 2-Benzotriazol-1-yl-2-pyrrol-1-yl-1-p-tolyl-ethanone 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 5467-70-9 2-amino-4'-methylacetophenone hydrochloride 

Relevant articles and documents

A new route to N-substituted heterocycles

N-(Benzotriazol-1-ylmethyl)-indole, - pyrrole, -carbazole, and -benzimidazole, and analogs substituted in the methylene group are converted by lithium aluminum hydride, or by Grignard reagents, or in two cases by organozinc reagents, into the N-substituted heterocycles in good yields.

Base-catalyzed rearrangement of α-benzotriazolyl alkoxide anions: Synthesis of one-carbon homologated α-substituted alkyl ketones

Deprotonated benzotriazole derivatives (1a-c) reacted with aldehydes to give the α-oxyanion substituted intermediates (2), which upon further treatment with butyllithium, without separation, resulted in the formation of one-carbon homologated α-substituted alkyl ketones (6a-f). Similar treatment of benzotriazole derivatives (1d-f) generated the benzotriazole ring-opening and rearranged products (7a-f). Plausible mechanisms for these reactions have been proposed.

A Facile and Convenient Synthesis of the Unknown 1-Aroylmethyl-1H-pyrroles

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