90554-53-3

Basic information

• Product Name: Pyridine, 3-methyl-2,5-diphenyl-
• CAS NO: 90554-53-3
• Molecular Formula: C18H15N
• Molecular Weight: 245.324
• Mol File: 90554-53-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pyridine, 3-methyl-2,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-methyl-2,5-diphenyl-(90554-53-3)
• EPA Substance Registry System: Pyridine, 3-methyl-2,5-diphenyl-(90554-53-3)

Safety Data

• Hazardous Substances Data: 90554-53-3(Hazardous Substances Data)

Upstream product

• 7182-09-4 N-(1-propenyl)piperidine 
• 64244-33-3 [1-Phenyl-meth-(E)-ylidene]-((E)-styryl)-amine 
• 769-60-8 2-methyl-1-phenylprop-2-en-1-one 
• 122-78-1 phenylacetaldehyde 

Relevant articles and documents

N-Silylenamines as Reactive Intermediates: Hydroamination for the Modular Synthesis of Selectively Substituted Pyridines

A modular and selective synthesis of mono-, di-, tri-, tetra-, and pentasubstituted pyridines is reported. Hydroamination of alkynes with N-silylamine using a bis(amidate)bis(amido)titanium(IV) precatalyst furnishes the regioselective formation of N-silylenamines. Addition of α,β-unsaturated carbonyls to the crude mixtures followed by oxidation affords 47 examples of pyridines in yields of up to 96%. This synthetic route allows for the synthesis of diverse pyridines containing variable substitution patterns, including pharmaceutically relevant 2,4,5-trisubstituted pyridines, using this one-pot protocol.

Cross Mannich Reaction of Aldehydes; Efficient Synthesis of Substituted Pyridines

Symmetrically and unsymmetrically substituted pyridines were obtained in highly efficient one-pot procedures starting from α-unbranched aldehydes and iminium salts.