90560-10-4

Basic information

• Product Name: 6-Methoxybenzo(b)thiophene
• Synonyms: 6-Methoxybenzo(b)thiophene;Benzo[b]thiophene, 6-Methoxy-;6-Methoxybenzothiophene
• CAS NO: 90560-10-4
• Molecular Formula: C₉H₈OS
• Molecular Weight: 164.22422
• Mol File: 90560-10-4.mol
• Article Data: 35

Chemical Properties

• Melting Point: 38-39 °C
• Boiling Point: 268.874°C at 760 mmHg
• Flash Point: 116.411°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 0.012mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 6-Methoxybenzo(b)thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxybenzo(b)thiophene(90560-10-4)
• EPA Substance Registry System: 6-Methoxybenzo(b)thiophene(90560-10-4)

Safety Data

• Hazardous Substances Data: 90560-10-4(Hazardous Substances Data)

Usage

General Description

6-Methoxybenzo(b)thiophene is a chemical compound that belongs to the group of benzo[b]thiophenes, which are aromatic heterocyclic compounds containing a benzene ring fused to a thiophene ring. It is a derivative of benzo[b]thiophene with a methoxy group attached to the benzene ring. 6-Methoxybenzo(b)thiophene is commonly used as a building block in organic synthesis and in the pharmaceutical industry for the production of various drugs. It exhibits interesting biological activities and is also used as a starting material for the synthesis of other valuable compounds. Additionally, 6-Methoxybenzo(b)thiophene also has applications in the field of materials science for the development of organic electronic and optoelectronic devices.

InChI:InChI=1/C9H8OS/c1-10-8-3-2-7-4-5-11-9(7)6-8/h2-6H,1H3

Upstream product

• 5858-22-0 2,3-dihydro-6-methoxybenzo[b]thiophen-3-one 
• 15570-12-4 3-methoxybenzenethiol 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 17347-32-9 6-bromobenzothiophene 
• 124-41-4 sodium methylate 
• 102539-79-7 6-methoxybenzo[b]thiophene-2-carboxylic acid 
• 187753-62-4 ethyl 6-methoxybenzo[b]thiophene-2-carboxylate 
• 331-64-6 2-fluoro-4-methoxy-benzaldehyde 
• 96803-85-9 1-[(2,2-diethoxyethyl)sulfanyl]-3-methoxybenzene 
• 105126-91-8 (3-methoxyphenylsulphanyl)acetaldehyde 
• 144-55-8 sodium hydrogencarbonate 
• 96803-64-4 2-(2-methoxythiophenoxy)acetaldehyde diethyl acetal 
• 3996-32-5 [(3-methoxyphenyl)sulfanyl]acetic acid 
• 596805-19-5 N,N-diethyl-2-methylsulfanyl-4-methoxybenzamide 

Downstream Products

• 193964-15-7 6-methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophene 
• 862082-02-8 1-{2-[4-(6-methoxy-benzo[b]thiophen-3-yloxy)-phenoxy]-ethyl}-piperidine 
• 862082-01-7 1-{2-[4-(6-methoxy-1,1-dioxo-1H-1λ6-benzo[b]thiophen-3-yloxy)-phenoxy]-ethyl}-piperidine 
• 862081-97-8 6-methoxy-3-[4-(2-piperidin-1-yl-ethoxy)-phenoxy]-2-bromobenzo[b]thiophene 
• 862082-00-6 1-{2-[4-(2-bromo-6-methoxy-1,1-dioxo-1H-1λ6-benzo[b]thiophen-3-yloxy)-phenoxy]-ethyl}-piperidine 
• 43121-88-6 6-methoxy-benzo[b]thiophene-3-carboxylic acid 
• 1093631-86-7 methyl 6-(4-hydroxyphenyl)-1-benzothiophene-3-carboxylate 
• 1093631-87-8 methyl 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-benzothiophene-3-carboxylate 
• 1093631-52-7 6-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-benzothiophene-3-carboxylic acid 
• 182133-35-3 6-methoxy-benzo[b]thiophen-2-yl boronic acid 
• 102539-79-7 6-methoxybenzo[b]thiophene-2-carboxylic acid 
• 19301-39-4 1-benzothiophen-6-ol 
• 414861-52-2 6-methoxy-2-(3-methoxyphenyl)benzo[b]thiophene 

Relevant articles and documents

Enantioselective hydroarylation or hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes

An efficient protocol for the asymmetric hydroarylation and hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes has been developed. The combination of a rhodium(I) precatalyst and a chiral diene ligand constitutes the catalytic system, which enables the facile synthesis of 2,3-dihydrobenzo[b]thiophene 1,1-dioxides in good yields with high enantioselectivities. The merging of this asymmetric hydroarylation with the downstream alkylations delivers 2,3-dihydrobenzo[b]thiophene 1,1-dioxides that contain two continuous quaternary stereocenters with high enantioselectivities in a diastereodivergent manner.

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