90690-76-9Relevant articles and documents
Ammonium nitrate: A biodegradable and efficient catalyst for the direct amidation of esters under solvent-free conditions
Ramesh, Perla,Fadnavis, Nitin W.
supporting information, p. 138 - 140 (2015/02/19)
A simple, metal-free, and environment-friendly procedure is developed for the direct conversion of esters to amides using ammonium nitrate as a catalyst under solvent-free conditions. Aryls, heteroaryls, and aliphatic esters are easily converted to the corresponding amides in excellent isolated yields (85-99%). An enantiopure ester and amine were both shown to react without racemization. The methodology has been successfully applied to preparation of procainamide.
N-[hydroxy(amino)alkyl]amides of amino(nitro)benzoic acids
Bagrov,Vasil'ev,Efimov,Kol'tsov
, p. 674 - 678 (2007/10/03)
2-Aminoethanol and 3-amino-1-propanol react with methyl 3-nitro-and 4-nitrobenzoates in boiling toluene to afford the corresponding ethyl N-(hydroxyalkyl)nitrobenzoates. The reaction of methyl 3-nitro-and 4-nitrobenzoates with bis(2-hydroxyethyl)amine yie