90726-82-2

Basic information

• Product Name: Butanoic acid, 2-(aminomethyl)-2-ethyl-, ethyl ester
• Synonyms: Butanoic acid,2-(aminomethyl)-2-ethyl-,ethyl ester;2-Aethyl-2-aminomethyl-buttersaeure-aethylester;2,2-Diaethyl-3-amino-propionsaeure-aethylester;3-Amino-2,2-diaethyl-propionsaeure-aethylester;ethyl 2-aminomethyl-2-ethylbutyrate;2-ethyl-2-aminomethyl-butyric acid ethyl ester
• CAS NO: 90726-82-2
• Molecular Formula: C9H19NO2
• Molecular Weight: 173.25300
• Mol File: 90726-82-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 94 °C(Press: 12 Torr)
• Density: 0.940±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Butanoic acid, 2-(aminomethyl)-2-ethyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 2-(aminomethyl)-2-ethyl-, ethyl ester(90726-82-2)
• EPA Substance Registry System: Butanoic acid, 2-(aminomethyl)-2-ethyl-, ethyl ester(90726-82-2)

Safety Data

• Hazardous Substances Data: 90726-82-2(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 7647-01-0 hydrogenchloride 
• 1619-56-3 ethyl 2-ethyl-2-cyanobutyrate 
• 91-17-8 decalin 

Downstream Products

• 16006-10-3 3,3-diethylazetidin-2-one 
• 204514-21-6 2-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-ethylbutanoic acid 

Relevant articles and documents

Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from N-(pent-2-en-4-ynyl)-β-lactams

(Chemical Equation Presented) Au-catalyzed synthesis of 5,6-dihydro-8H-indolizin-7-ones from readily available N-(pent-2-en-4-ynyl)- β-lactams is developed. In this reaction, a 5-exo-dig cyclization of the β-lactam nitrogen to the Au-activated C-C triple bond is followed by heterolytic fragmentation of the amide bond, forming a highly nucleophilic acyl cation. An expedient formal synthesis of indolizidine 167B was easily achieved using this new method.

ACYL COMPOUNDS

Compounds of the formula STR1 in which R 1 is an aliphatic hydrocarbon radical which is unsubstituted or substituted by halogen or hydroxyl, or a cycloaliphatic or araliphatic hydrocarbon radical; X 1 is CO, SO 2, or--O--C(=O)--with the carbon atom of the carbonyl group being attached to the nitrogen atom shown in formula I; X 2 is a divalent aliphatic hydrocarbon radical which is unsubstituted or substituted by hydroxyl, carboxyl, amino, guanidino or a cycloaliphatic or aromatic radical, or is a divalent cycloaliphatic hydrocarbon radical, it being possible for a carbon atom of the aliphatic hydrocarbon radical to be additionally bridged by a divalent aliphatic hydrocarbon radical; R. sub.2 is carboxyl which, if desired, is esterified or amidated, substituted or unsubstituted amino, formyl which, if desired, is acetalized, 1H-tetrazol-5-yl, pyridyl, hydroxyl which, if desired, is etherified, S(O) m--R where m is 0, 1 or 2 and R is hydrogen or an aliphatic hydrocarbon radical, alkanoyl, unsubstituted or N-substituted sulfamoyl or PO n H 2 where n is 2 or 3; X 3 is a divalent aliphatic hydrocarbon; R 3 is carboxyl, 5-tetrazolyl, SO. sub.3 H, PO. sub.2 H 2, PO 3 H 2 or haloalkylsulfamoyl; and the rings A and B independently of one another are substituted or unsubstituted; in free form or in salt form, can be prepared in a manner known per se and can be used, for example, as medicament active ingredients.