908267-63-0 Usage
Description
4-bromo-2-isopropylpyridine is a chemical compound with the molecular formula C10H12BrN. It is an aromatic organobromine compound featuring a bromine atom attached to the 4th carbon of a pyridine ring and an isopropyl group attached to the 2nd carbon. 4-bromo-2-isopropylpyridine serves as a crucial intermediate in the synthesis of various pharmaceuticals and agrochemicals, playing a significant role in medicinal chemistry and drug discovery due to its versatility as a precursor to a broad spectrum of bioactive molecules.
Uses
Used in Pharmaceutical Industry:
4-bromo-2-isopropylpyridine is utilized as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new chemical entities that can address unmet medical needs and contribute to advancements in healthcare.
Used in Agrochemical Industry:
4-bromo-2-isopropylpyridine also serves as an important building block in the creation of agrochemicals, which are essential for enhancing crop protection and ensuring sustainable agricultural practices.
Used in Organic Synthesis:
4-bromo-2-isopropylpyridine is employed as a versatile reactant in organic synthesis reactions, enabling the production of a wide range of chemical compounds with diverse applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 908267-63-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,8,2,6 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 908267-63:
(8*9)+(7*0)+(6*8)+(5*2)+(4*6)+(3*7)+(2*6)+(1*3)=190
190 % 10 = 0
So 908267-63-0 is a valid CAS Registry Number.
908267-63-0Relevant articles and documents
Radical chain monoalkylation of pyridines
Dénès, Fabrice,Jangra, Harish,Meléndez, Camilo,Mulliri, Kleni,Renaud, Philippe,Rieder, Samuel,Zipse, Hendrik
, p. 15362 - 15373 (2021/12/14)
The monoalkylation of N-methoxypyridinium salts with alkyl radicals generated from alkenes (via hydroboration with catecholborane), alkyl iodides (via iodine atom transfer) and xanthates is reported. The reaction proceeds under neutral conditions since no acid is needed to activate the heterocycle and no external oxidant is required. A rate constant for the addition of a primary radical to N-methoxylepidinium >107 M-1 s-1 was experimentally determined. This rate constant is more than one order of magnitude larger than the one measured for the addition of primary alkyl radicals to protonated lepidine demonstrating the remarkable reactivity of methoxypyridinium salts towards radicals. The reaction has been used for the preparation of unique pyridinylated terpenoids and was extended to a three-component carbopyridinylation of electron-rich alkenes including enol esters, enol ethers and enamides.
2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS
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Page/Page column 157, (2014/08/19)
The present invention provides 2,6,7,8 Substituted Purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions compris
