90921-94-1 Usage
Description
(1E)-5-methoxy-2,3-dihydro-1H-inden-1-one oxime, also known as zardaverine, is a chemical compound belonging to the oxime family. It is a potent and selective inhibitor of phosphodiesterase type IV (PDE4), which is crucial in regulating intracellular cyclic adenosine monophosphate (cAMP) levels.
Used in Pharmaceutical Industry:
(1E)-5-methoxy-2,3-dihydro-1H-inden-1-one oxime is used as a therapeutic agent for the treatment of various diseases, including asthma, chronic obstructive pulmonary disease (COPD), and inflammatory disorders. Its ability to inhibit PDE4 makes it a promising candidate for the development of new drugs targeting these conditions.
Used in Drug Development:
(1E)-5-methoxy-2,3-dihydro-1H-inden-1-one oxime is used as a lead compound in drug development for the creation of new pharmaceuticals that can effectively manage conditions related to PDE4 dysregulation.
Further research is needed to fully understand the pharmacological properties and potential clinical applications of (1E)-5-methoxy-2,3-dihydro-1H-inden-1-one oxime, ensuring its safety and efficacy in treating the aforementioned diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 90921-94-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,9,2 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 90921-94:
(7*9)+(6*0)+(5*9)+(4*2)+(3*1)+(2*9)+(1*4)=141
141 % 10 = 1
So 90921-94-1 is a valid CAS Registry Number.
90921-94-1Relevant articles and documents
POTENT SMALL MOLECULE INHIBITORS OF AUTOPHAGY, AND METHODS OF USE THEREOF
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Page/Page column 70; 71, (2014/09/29)
Certain aspects of the invention relate to small molecule autophagy inhibitors, and their use for treatment and prevention of cancers and acute pancreatitis. Medicinal chemistry studies led to small molecular autophagy inhibitors with improved potency and selectivity.
(FUSED RING ARYLAMINO AND HETEROCYCLYLAMINO) PYRIMIDYNYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR USE IN TREATING PROLIFERATIVE DISEASES
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Page/Page column 79, (2012/10/18)
Provided herein are (fused ring arylamino and heterocyclylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, e.g., a compound of Formula (I), and their pharmaceutical compositions, preparation, and use as agents or drugs for treating proliferative diseases.
