90923-05-0

Basic information

• Product Name: Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)-
• CAS NO: 90923-05-0
• Molecular Formula: C10H11NO5
• Molecular Weight: 225.201
• Mol File: 90923-05-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)-(90923-05-0)
• EPA Substance Registry System: Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)-(90923-05-0)

Safety Data

• Hazardous Substances Data: 90923-05-0(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)- is a chemical compound with the molecular formula C11H13NO6. It is a yellow crystalline powder that is commonly used in organic synthesis and biochemical research. Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)- is known for its nitro and methoxy functional groups, which contribute to its unique properties and reactivity. It is often utilized as a building block in the synthesis of various pharmaceuticals, dyes, and other organic compounds. Additionally, Ethanone, 1-(3,6-dimethoxy-2-nitrophenyl)- has been studied for its potential biological activities, including antimicrobial and antioxidant properties.

Upstream product

• 1201-38-3 2',5'-dimethoxyacetophenone 
• 101288-18-0 (3,6-dimethoxy-2-nitro-benzoyl)-malonic acid diethyl ester 

Downstream Products

• 100193-39-3 4-(3,6-dimethoxy-2-nitro-phenyl)-4-oxo-butyric acid 
• 99990-38-2 3-bromo-4-(3,6-dimethoxy-2-nitro-phenyl)-4-oxo-butyric acid 
• 108711-19-9 (2-Acetyl-3,6-dimethoxy-phenyl)-carbamic acid ethyl ester 
• 234752-09-1 2-amino-5-bromo-3,6-dimethoxyacetophenone 
• 98300-35-7 2-amino-3,6-dimethoxyacetophenone 

Relevant articles and documents

Studies on quinones: Part 30. Synthesis of benzo[b]thiophene-4,7- quinones

The synthesis of a variety of benzo[b]thiophene-4,7-quinones (4a-f) by oxidative demethylation of the corresponding 4,7-dimethoxybenzo[b]thiophenes (3a-f) with cerium (IV) ammonium nitrate is reported. Heterocycles (3a,b) were prepared by cyclization of t

Synthesis and Cardiotonic Activity of a Series of Substituted 4-Alkyl-2(1H)-quinazolinones

The synthesis, cardiac fraction III cyclic nucleotide phosphodiesterase (PDE-III) inhibition, and positive inotropic activity of a series of 2(1H)-quinazolinones are reported.A general synthesis of the series involved the cyclization of 2-aminoacetophenones with potassium cyanate in acetic acid.Modifications at the 4-position of the quinazoline nucleus were best achieved by formation of the intermediate N1-acyl-N3-phenylurea from the substituted phenyl isocyanate and appropriate carboxamide.PPA was used to ring close to the quinazoline product.Generally the SAR for the series paralleled the five-point model previously published for PDE-III inhibition.The most active analogue of the series was 5,6-dimethoxy-4-methyl-2(1H)-quinazolinone (1) (ORF 16600), which had about twice the intravenous potency of amrinone.Compound 1 is currently under development as an orally active cardiotonic.