909297-88-7 Usage
Description
(S)-tert-Butyl 1-(tert-butyldimethylsilyloxy)propan-2-ylcarbamate is a chemical compound utilized as a protecting group for amines in organic chemistry. It is a derivative of tert-butyl carbamate, featuring a tert-butyldimethylsilyloxy group that shields the amine functionality from undesired reactions during synthetic processes. (S)-tert-Butyl 1-(tert-butyldimethylsilyloxy)propan-2-ylcarbamate is particularly valuable in the synthesis of complex organic molecules, including amine-containing compounds, as it enables selective chemical reactions without interference with the amine group.
Uses
Used in Organic Synthesis:
(S)-tert-Butyl 1-(tert-butyldimethylsilyloxy)propan-2-ylcarbamate is used as a protecting group for amines in the field of organic synthesis to facilitate selective reactions without affecting the amine functionality.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-tert-Butyl 1-(tert-butyldimethylsilyloxy)propan-2-ylcarbamate is used as a synthetic intermediate for the development of various drugs, particularly those containing amine groups, due to its ability to protect these groups during the synthesis process.
Used in Chemical Research:
(S)-tert-Butyl 1-(tert-butyldimethylsilyloxy)propan-2-ylcarbamate is also used as a research tool in chemical laboratories for studying the reactivity and properties of amine-containing compounds, as well as for developing new synthetic methods and strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 909297-88-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,0,9,2,9 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 909297-88:
(8*9)+(7*0)+(6*9)+(5*2)+(4*9)+(3*7)+(2*8)+(1*8)=217
217 % 10 = 7
So 909297-88-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H31NO3Si/c1-11(15-12(16)18-13(2,3)4)10-17-19(8,9)14(5,6)7/h11H,10H2,1-9H3,(H,15,16)
909297-88-7Relevant articles and documents
New building block for polyhydroxylated piperidine: Total synthesis of 1,6-dideoxynojirimycin
Rengasamy, Rajesh,Curtis-Long, Marcus J.,Woo, Duck Seo,Seong, Hun Jeong,Jeong, Ill-Yun,Ki, Hun Park
, p. 2898 - 2901 (2008/09/19)
(Chemical Equation Presented) (3R,4S)-3-Hydroxy-4-N-allyl-N-Boc-amino-1- pentene 10, an important precursor for the synthesis of polyhydroxylated piperidines, has been achieved as a single diastereomer without racemization via vinyl Grignard addition to N-Boc-N-allyl aminoaldehyde 9, which was derived from an enantiopure natural amino acid. Having forged a tetrahydropyridine ring scaffold 13 from 10 in 85% yield via RCM using Grubbs II catalyst, we were able to effect its stereodivergent dihydroxylation, via a common epoxide intermediate to yield a range of interesting hydroxylated piperidines, including ent-1,6-dideoxynojirimycin (ent-1,6-dDNJ) 1 (28% overall yield) and 5-amino-1,5,6-trideoxyaltrose 2 (29% over all yield) in excellent dr. To the best of our knowledge, our synthesis of ent-1,6-dDNJ 1 is the most expeditious to date.
