909649-06-5

Basic information

• Product Name: 5-BROMO-8-CHLORO-1,7-NAPHTHYRIDINE(MINIMUM90%)
• Synonyms: 5-BROMO-8-CHLORO-1,7-NAPHTHYRIDINE(MINIMUM90%) ;5-broMo-8-chloro-1;5-Bromo-8-chloro-1,7-naphthyridine90%
• CAS NO: 909649-06-5
• Molecular Formula: C₈H₄BrClN₂
• Molecular Weight: 243.48776
• Product Categories: CHIRAL CHEMICALS
• Mol File: 909649-06-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 343.5 °C at 760 mmHg
• Flash Point: 161.5 °C
• Appearance: /
• Density: 1.762 g/cm³
• Vapor Pressure: 0.00014mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -0.14±0.30(Predicted)
• CAS DataBase Reference: 5-BROMO-8-CHLORO-1,7-NAPHTHYRIDINE(MINIMUM90%)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-8-CHLORO-1,7-NAPHTHYRIDINE(MINIMUM90%)(909649-06-5)
• EPA Substance Registry System: 5-BROMO-8-CHLORO-1,7-NAPHTHYRIDINE(MINIMUM90%)(909649-06-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 909649-06-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-8-chloro-1,7-naphthyridine, with a minimum purity of 90%, is a chemical compound used in various industrial and research applications. It is a naphthyridine derivative, which can be used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Its unique molecular structure and functional groups make it valuable for the development of new drugs, insecticides, and other biologically active molecules. This chemical may also be used in the study of biological processes and in the development of new materials. Careful handling and storage of 5-Bromo-8-chloro-1,7-naphthyridine are essential due to its potential reactivity and toxicity.

InChI:InChI=1/C8H4BrClN2/c9-6-4-12-8(10)7-5(6)2-1-3-11-7/h1-4H

Upstream product

• 17965-82-1 8-amino-1,7-naphthyridine 
• 452-58-4 2,3-Diaminopyridine 
• 67967-17-3 8-amino-5-bromo-1,7-naphthyridine 

Downstream Products

• 17965-76-3 5-bromo-1,7-naphthyridine 

Relevant articles and documents

ALPHA, BETA-UNSATURATED AMIDE COMPOUND

An object of the present invention is to provide an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like. The α,β-unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt or the like thereof has anticancer activity and the like: [wherein, "A" represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents -O-, -S-, -SO2-, -NRX1- (wherein, RX1 represents hydrogen atom or lower alkyl), -CHRX2- (wherein, RX2 represents hydrogen atom or hydroxy), -CH=CH-, -CO- or -NH-CO-, and n1 and n2 are the same or different, and each represents 0 or 1].

Naphthyridin derivatives

The present invention relates to heterocyclic derivatives of formula I wherein R1, R2 and R3 are as defined in the description and claims, which compounds are metabotropic glutamate receptor 5 antagonists.