909776-51-8Relevant articles and documents
INDOLE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF IN PHARMACEUTICAL DRUG
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Paragraph 0101; 0102, (2018/07/06)
An indole derivative as expressed by Formula (I), a preparation method thereof, a pharmaceutical salt, and use thereof as a therapeutic agent, especially as a FGFR inhibitor. Each substituent in Formula (I) has identical definition as specified in the specification.
Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: Synthesis and pharmacological evaluation
Ongarora, Dennis S.B.,Gut, Jiri,Rosenthal, Philip J.,Masimirembwa, Collen M.,Chibale, Kelly
scheme or table, p. 5046 - 5050 (2012/09/07)
The synthesis and evaluation of antiplasmodial activity of benzothiazole, benzimidazole, benzoxazole and pyridine analogues of amodiaquine is hereby reported. Benzothiazole and benzoxazole analogues with a protonatable tertiary nitrogen atom possessed excellent activity against the W2 and K1 chloroquine resistant strains of Plasmodium falciparum, with IC50s ranging from 7 to 22 nM.
AMINO-SUBSTITUTED 8-N-BENZIMIDAZOLES AND METHODS FOR THEIR USE IN BLOOD SUGAR DISORDERS
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Page/Page column 11, (2008/06/13)
The present invention comprises the use of amino-substituted 8-N-benzimidazoles compounds of formula I wherein R3, R4-R5, R11 and R20-R21 are hereinafter defined which display a therapeutically utilizable blood sugar-lowering action. These compounds are i