910134-41-7Relevant articles and documents
A microwave approach to the synthesis of certain 4-(substituted phenyl)-6-phenyl-3-cyano-2-pyridones
Marinkovic, Aleksandar,Mijin, Du?an,Mirkovic, Jelena,Maslak, Veselin,Kappe, C. Oliver
, p. 759 - 765 (2014/11/27)
A study of the synthesis of 4-(substituted phenyl)-6-phenyl-3-cyano- 2-pyridones from ethyl 2-cyano-3-(substituted phenyl) acrylates and acetophenone is presented. The 2-pyridones were obtained using conventional as well as microwave synthesis under solvent and solvent-free conditions in domestic and laboratory microwave ovens. The structure of the obtained pyridones was confirmed by m.p., FT-IR, NMR and UV data.
Synthesis and biological screening of some pyridine derivatives as anti-malarial agents
Bekhit, Adnan A.,Hymete, Ariaya,Damtew, Ashenafi,Mohamed, Abdel Maaboud I.,Bekhit, Alaa El-Din A.
experimental part, p. 69 - 77 (2012/04/05)
Two series of pyridine derivatives were synthesised and evaluated for their in vivo anti-malarial activity against Plasmodium berghei. The anti-malarial activity was determined in vivo by applying 4-day standard suppressive test using chloroquine (CQ)-sen