910138-96-4 Usage
Description
R-DULOXETINE HYDROCHLORIDE, also known as (R)-Duloxetine hydrochloride, is a napthalenyloxy-substituted amine that is a white solid. It is used in binding studies of human serum albumin along with its enantiomer, (S)-Duloxetine. However, unlike its enantiomer, R-DULOXETINE HYDROCHLORIDE is not a very effective dual serotonin and norepinephrine reuptake inhibitor (SNRI).
Uses
Used in Pharmaceutical Industry:
R-DULOXETINE HYDROCHLORIDE is used as a binding agent in human serum albumin studies for understanding its interactions and properties.
Used in Research and Development:
R-DULOXETINE HYDROCHLORIDE is used as a research compound to study its chemical properties and compare its effectiveness with its enantiomer, (S)-Duloxetine, in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 910138-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,1,3 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 910138-96:
(8*9)+(7*1)+(6*0)+(5*1)+(4*3)+(3*8)+(2*9)+(1*6)=144
144 % 10 = 4
So 910138-96-4 is a valid CAS Registry Number.
910138-96-4Relevant articles and documents
Process for the Preparation of 1-Naphthol Mixed Ethers and Intermediates of Crystalline Forms of (+) and (-)-Duloxetine
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Page/Page column 3, (2008/12/09)
The invention relates to a process for the preparation of duloxetine (1a), comprising the reaction between 1-fluoronaphthalene and 3-N,N-dimethylamino-1-(2-thienyl)-propan-1-ol in the presence of 1,3-dimethyl-2-oxo-hexahydropyrimidine (DMPU) as the solvent; a method for the identification of duloxetine enantiomers and for the determination of its optical purity is also disclosed.
