910223-93-7

Basic information

• Product Name: methyl 2-[2-(methoxycarbonyl)phenyl]-2-(2-nitrophenyl)acetate
• Synonyms: methyl 2-[2-(methoxycarbonyl)phenyl]-2-(2-nitrophenyl)acetate
• CAS NO: 910223-93-7
• Molecular Weight: 329.309
• Mol File: 910223-93-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 2-[2-(methoxycarbonyl)phenyl]-2-(2-nitrophenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-[2-(methoxycarbonyl)phenyl]-2-(2-nitrophenyl)acetate(910223-93-7)
• EPA Substance Registry System: methyl 2-[2-(methoxycarbonyl)phenyl]-2-(2-nitrophenyl)acetate(910223-93-7)

Safety Data

• Hazardous Substances Data: 910223-93-7(Hazardous Substances Data)

Upstream product

• 716-43-8 dimethyl homophthalate 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 58821-75-3 2-[(2-aminophenyl)methyl]benzoic acid 
• 1211-06-9 5,11-dihydro-6H-dibenz[b,e]azepin-6-one 
• 37829-66-6 2-[(2-nitrophenyl)methyl]benzoic acid 

Relevant articles and documents

Dibenzo-fused seven-membered nitrogen heterocycles by a tandem reduction-lactamization reaction

Efficient syntheses of dibenz[b,f][1,4]oxazepin-11(10H)-one, 5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one and 5,11-dihydro-6H-dibenz[b, e]azepin-6-one are described using a tandem reduction-lactamization sequence. Precursors for these ring systems are available in 1-3 steps using nucleophilic aromatic substitution and Ullmann coupling methodology. Direct reduction-lactamization of these compounds using iron powder in acetic acid at 115° affords the target heterocycles in ≥90% yield.